Mortalidad asociada a injuria renal aguda en pacientes hospitalizados por covid-19 severo del hospital Santa rosa, Piura, 2021

Abstract

OBJETIVO: Evaluar la mortalidad asociada a injuria renal aguda en pacientes hospitalizados.por. COVID-19 severo.en.el.hospital.Santa.Rosa,.Piura,.2021. MATERIAL.Y.MÉTODO: Se realizó un estudio cohorte retrospectivo en pacientes con COVID-19 severo. La recolección de información se realizó mediante una ficha de recolección. Se incluyeron adultos con COVID-19 severo y se obtuvieron dos cohortes según criterios de Injuria renal aguda por la guía KDIGO. RESULTADOS: La cohorte de estudio tuvo 37 integrantes y la cohorte de control 180. El sexo femenino es un factor protector para injuria renal aguda (RR: 0.368; p=0.029; IC 95%:1.031 - 1.286). El tener más de 65 años es factor de riesgo para desarrollar injuria renal aguda (RR: 2.538; p: 0.0016; IC 95%:1.402 – 4.596). La mortalidad en la cohorte de estudio fue 86.5% y en la cohorte de comparación 34.4% (RR: 2.511; p: <0.0001; IC 95% 1.978 – 3.187) CONCLUSIÓN: La.mortalidad en pacientes con COVID-19 severo que hacen injuria renal aguda es mayor que en quienes no hacen injuria renal aguda. El sexo femenino y el tener menos de 65 años de edad, son factores protectores para no desarrollar injuria renal aguda. PALABRAS CLAVE: Injuria renal aguda, COVID-19, mortalidad.

OBJECTIVE: To assess mortality associated with acute kidney injury in hospitalized patients.by.severe.COVID-19.at.the.Santa.Rosa.hospital,.Piura,.2021. MATERIAL AND METHOD: A retrospective cohort study was conducted in patients with severe COVID-19. The collection of information was carried out through a collection form. Adults with severe COVID-19 were included and two cohorts were obtained according to the criteria for acute kidney injury by the KDIGO guide. RESULTS: The study cohort had 37 members and the control cohort 180. Female gender is a protective factor for acute kidney injury (RR: 0.368; p=0.029; 95% CI: 1.031 - 1.286). Being older than 65 years is a risk factor for developing acute kidney injury (RR: 2.538; p: 0.0016; 95% CI: 1.402 – 4.596). Mortality in the study cohort was 86.5% and in the comparison cohort 34.4% (RR: 2.511; p: <0.0001; 95% CI 1.978 – 3.187) CONCLUSION: Mortality in patients with severe COVID-19 who do acute kidney injury is higher than in those who do not do acute kidney injury. Being female and being under 65 years of age are protective factors against developing acute kidney injury. KEY WORDS: Acute kidney injury, COVID-19, mortality.