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Casas, V., (2018). Asociación entre el periodo intergenésico y trastornos del espectro autista [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/3934
Casas, V., Asociación entre el periodo intergenésico y trastornos del espectro autista [Tesis]. : Universidad Privada Antenor Orrego - UPAO; 2018. https://hdl.handle.net/20.500.12759/3934
@misc{renati/377081,
title = "Asociación entre el periodo intergenésico y trastornos del espectro autista",
author = "Casas Latorre, Vania Antonella",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2018"
}
Title: Asociación entre el periodo intergenésico y trastornos del espectro autista
Authors(s): Casas Latorre, Vania Antonella
Advisor(s): Lozada Cáceda, Jorge Antonio
Issue Date: 2018
Institution: Universidad Privada Antenor Orrego - UPAO
Abstract: Objetivo: Determinar la asociación entre el periodo intergenésico corto y largo y
la presencia de desórdenes del espectro autista en el Hospital Belén de Trujillo
2010-2016.
Material y métodos: Se realizó un estudio analítico, retrospectivo de casos y
controles en 256 pacientes pediátricos atendidos en el Hospital Belén de Trujillo
durante el periodo 2010 – 2016 distribuidos en 128 casos y 128 controles. Se
evalúo las variables de Periodo intergenésico (PIG) corto y largo, así mismo
posibles variables confusoras. El análisis estadístico se realizó mediante Chi-
cuadrado y cálculo de Odds Ratio.
Resultados: Se evaluaron un total de 256 pacientes, no se encontró diferencia
significativa para sexo, edad materna, edad paterna, hipertensión arterial
materna, diabetes materna y parto por cesárea. Se halló diferencia significativa
para la edad actual y la edad gestacional al nacimiento (p:<0.001, p: 0.014). PIG
corto y PIG largo obtuvieron asociación significativa con el desarrollo de TEA,
(OR: 2.45, IC: 1,026-5,871; OR: 2.17 IC: 1,821- 4,379 respectivamente). El resto
de covariables no mostró asociación significativa.
Conclusión: Los periodos intergenésicos corto y largo son factores de riesgo
independientes asociados al desarrollo de trastornos del espectro autista.
Objective: To determine the association between the short and long intergenic period and the presence of autistic spectrum disorders and in the ““Hospital Belen de Trujillo 2010-2016““. Material and methods: An analytical, retrospective study of cases and controls was carried out. 256 pediatric patients attended in the Belen Hospital of Trujillo during the period 2010-2016. Distributed in 128 cases and 128 controls. The variables of the short and long intergenic period were evaluated, as well as possible confounding variables. Statistical analysis was performed using Chi -square and Odds Ratio calculation. Results: 256 patients were evaluated; no significant difference was found for sex, maternal age, paternal age, maternal hypertension, maternal diabetes and cesarean delivery. Significant difference was found for current age and gestational age at birth (p: <0.001, p: 0.014). The short intergenic period and the long intergenic period obtained a significant association with the development of ASD, (OR: 2.45, IC: 1,026-5,871; OR: 2.17 IC: 1,821- 4,379 respectively). The rest of the covariates showed no significant association. Conclusion: The short and long intergenic periods are independent risk factors associated with the development of autistic spectrum disorders with an OR: 2.45 (CI: 1.026-5.871) and OR: 2.17 (CI: 1.821- 4.379) respectively.
Objective: To determine the association between the short and long intergenic period and the presence of autistic spectrum disorders and in the ““Hospital Belen de Trujillo 2010-2016““. Material and methods: An analytical, retrospective study of cases and controls was carried out. 256 pediatric patients attended in the Belen Hospital of Trujillo during the period 2010-2016. Distributed in 128 cases and 128 controls. The variables of the short and long intergenic period were evaluated, as well as possible confounding variables. Statistical analysis was performed using Chi -square and Odds Ratio calculation. Results: 256 patients were evaluated; no significant difference was found for sex, maternal age, paternal age, maternal hypertension, maternal diabetes and cesarean delivery. Significant difference was found for current age and gestational age at birth (p: <0.001, p: 0.014). The short intergenic period and the long intergenic period obtained a significant association with the development of ASD, (OR: 2.45, IC: 1,026-5,871; OR: 2.17 IC: 1,821- 4,379 respectively). The rest of the covariates showed no significant association. Conclusion: The short and long intergenic periods are independent risk factors associated with the development of autistic spectrum disorders with an OR: 2.45 (CI: 1.026-5.871) and OR: 2.17 (CI: 1.821- 4.379) respectively.
Link to repository: https://hdl.handle.net/20.500.12759/3934
Discipline: Medicina Humana
Grade or title grantor: Universidad Privada Antenor Orrego. Facultad de Medicina Humana
Grade or title: Médico Cirujano
Register date: 10-Apr-2018
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