Citas bibligráficas
Irala, A., (2024). Fenotipo clínico según sexo de pacientes con síndrome coronario agudo en el departamento de emergencia de un hospital nivel III-1 en Perú [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/15697
Irala, A., Fenotipo clínico según sexo de pacientes con síndrome coronario agudo en el departamento de emergencia de un hospital nivel III-1 en Perú []. PE: Universidad Peruana Cayetano Heredia; 2024. https://hdl.handle.net/20.500.12866/15697
@misc{renati/686708,
title = "Fenotipo clínico según sexo de pacientes con síndrome coronario agudo en el departamento de emergencia de un hospital nivel III-1 en Perú",
author = "Irala Lazo, Antonella Lilia",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2024"
}
Background: Differences are observed in the presentation, treatment and prognosis in acute coronary syndrome between both sexes. However, Latin American information on this is scarce. Objective: Identify the clinical phenotype according to sex in patients with acute coronary syndrome in the emergency department of a Level III-1 referral hospital in Lima, Peru. Materials and methods: Retrospective, observational and analytical study; The exposure variable was sex and the variables of interest were clinical presentation, treatment and prognosis. Sex was analyzed with the variables of interest using Chi square or Fisher's exact test in categorical variables and the student t test or Mann Whitney U test in continuous variables. Results: The mean age of the women was 65.0; and in men, 58.0. Women presented angina with atypical symptoms (30.3% vs 8%, p=0.002) and anxiety (12.1% vs 2.2%, p=0.045). They remained under observation (54.6% vs 27%, p=0.004) and had the first revascularization more than 12 hours later (73.3% vs 40%, p=0.024). Men received adequate doses of aspirin (77.5% vs 42.9%, p=0.001) and clopidogrel (73.4% vs 35.7%, p= <0.001); received thrombolysis (40.5% vs 6.1%, p<0.001), rescue angioplasty (14.6% vs 0%, p=0.019) and the first revascularization procedure between 60 to 120 minutes (24.6% vs 0%, p=0.033). Conclusion: The female clinical phenotype was older, presented angina with atypical symptoms, acute myocardial infarction without ST elevation, incorrect doses of antiplatelets, absence of thrombolysis and delay in revascularization.
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