Citas bibligráficas
Duran, C., Mogollón, S., Pulache, Á. (2021). Verificación del desempeño analítico de marcadores bioquímicos de función renal implementados en una plataforma automatizada en el servicio de laboratorio clínico de un hospital en Lima, Perú [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/11831
Duran, C., Mogollón, S., Pulache, Á. Verificación del desempeño analítico de marcadores bioquímicos de función renal implementados en una plataforma automatizada en el servicio de laboratorio clínico de un hospital en Lima, Perú []. PE: Universidad Peruana Cayetano Heredia; 2021. https://hdl.handle.net/20.500.12866/11831
@misc{renati/494019,
title = "Verificación del desempeño analítico de marcadores bioquímicos de función renal implementados en una plataforma automatizada en el servicio de laboratorio clínico de un hospital en Lima, Perú",
author = "Pulache Mauricio, Álvaro Renzo",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2021"
}
Background: Chronic kidney disease affects the life of 1 in 10 people worldwide and its incidence is increasing. This is why the clinical laboratory must issue reliable results for the diagnosis and follow-up of patients with renal diseases. This is achieved by using analytical methodologies that meet the technical specifications provided by their manufacturer. Objectives: Verify the analytical performance of the markers for renal function (creatinine, urea nitrogen, uric acid, urine proteins and microalbumin) implemented in the Dimension RXL Max automated system of the Naval Medical Center applying the CLSI EP 15 A3 guidelines. Then, compare the Total Errors of the methods with the Maximum allowable error (ETp) by CLIA and Biological Variability. Methods and Materials: A cross-sectional descriptive study was carried out. All runs were made according to EP 15 A3 guidelines for 2 levels of clinical decision reference materials. The data was analyzed using the statistical software Analyse-It and Microsoft Excel. Results: Repeatability and Intralaboratory precision were verified in all methods. However, the methods for urea and urine protein at normal level didn’t verify in trueness. Also, the total errors of both of these methods surpassed the ETp specified by CLIA. Conclusions: The methods for creatinine, uric acid and microalbumin can continue to be used. However, the manufacturer of the urea and urine protein methods should be contacted to correct the errors and then a new analytical performance verification should be made.
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