Bibliographic citations
Rodríguez, J., Martínez, C., Salazar, F., Bedón, S., Cisneros, D. (2021). Fisiopatología, manifestaciones clínicas y enfoque terapéutico de las complicaciones cardiovasculares asociadas a la infección por SARS-CoV-2: Una revisión narrativa [Trabajo de investigación, Universidad Peruana de Ciencias Aplicadas (UPC)]. http://hdl.handle.net/10757/667435
Rodríguez, J., Martínez, C., Salazar, F., Bedón, S., Cisneros, D. Fisiopatología, manifestaciones clínicas y enfoque terapéutico de las complicaciones cardiovasculares asociadas a la infección por SARS-CoV-2: Una revisión narrativa [Trabajo de investigación]. PE: Universidad Peruana de Ciencias Aplicadas (UPC); 2021. http://hdl.handle.net/10757/667435
@misc{renati/404462,
title = "Fisiopatología, manifestaciones clínicas y enfoque terapéutico de las complicaciones cardiovasculares asociadas a la infección por SARS-CoV-2: Una revisión narrativa",
author = "Cisneros Montoya, Daniel",
publisher = "Universidad Peruana de Ciencias Aplicadas (UPC)",
year = "2021"
}
Background: SARS-CoV-2 is a type of virus discovered in 2019, responsible for the coronavirus disease (COVID-19). As of September 19, 2021, out of 228 million confirmed cases, 4.6 million deaths have been reported globally. The cardiovascular system is one of the systems primarily affected in COVID-19 disease. Methods: An information search was carried out in four databases (Scopus, PubMed, Scielo and Google Scholar) and the articles that served for the present review were selected, which were included and ordered in Zotero. Results and Discussion: Several studies have identified the association between infection, by SARS-CoV-2 and cardiovascular damage, evidenced by the elevation of cardiac biomarkers, and identifying ACE-2 and a dysregulated systemic inflammatory process as pathophysiological mechanisms of the cardiovascular injury. It has been identified that the presence of cardiovascular diseases, especially arterial hypertension, and Diabetes Mellitus increase the risk of mortality and cardiovascular complications in SARS-CoV-2 infection. In addition to direct cardiac damage, manifesting as myocarditis, it was also associated with arrhythmias and thrombotic disorders. Regarding the drugs used to treat cardiovascular complications, benefits were found with the use of anticoagulant drugs, inotropics, ACEIs, AIIRAs and the use of cardioversion in the case of arrhythmias. Conclusions: The relationship between SARS-CoV-2 and the cardiovascular system was evidenced, based on the pathophysiological mechanisms, its clinical manifestations and alternatives for its treatment.
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