Citas bibligráficas
Bravo, J., (2024). Factores clínicos asociados a la eficacia del tratamiento fibrinolítico en pacientes con IAMCEST que acuden a la emergencia en los últimos 5 años [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/28991
Bravo, J., Factores clínicos asociados a la eficacia del tratamiento fibrinolítico en pacientes con IAMCEST que acuden a la emergencia en los últimos 5 años [Tesis]. PE: Universidad Privada Antenor Orrego; 2024. https://hdl.handle.net/20.500.12759/28991
@misc{renati/381386,
title = "Factores clínicos asociados a la eficacia del tratamiento fibrinolítico en pacientes con IAMCEST que acuden a la emergencia en los últimos 5 años",
author = "Bravo Avilés, Juan Carlos",
publisher = "Universidad Privada Antenor Orrego",
year = "2024"
}
Objetives: To identify the clinical factors associated with the efficacy of fibrinolytic treatment in patients with ST-segment elevation myocardial infarction (STEMI) in the emergency department of Cayetano Heredia Hospital between 2019 and 2023. Materials and Methods: An analytical cross-sectional study was conducted. Data were collected from patients' medical records, and SPSS 27 software was utilized for analysis. Univariate analysis results are presented using percentage frequencies or mean and standard deviation, depending on the categorical or numerical nature of the data. Chi-square or Mann-Whitney U and Wilcoxon tests were employed in multivariate analysis based on the normality of distribution. ROC curves were generated to identify cutoff points. Results: A total of 80 patients participated, with an average age of 62 years. 90% were male, 58.8% had hypertension (HTA), 28.8% had diabetes mellitus (DM), and 7.5% had a previous myocardial infarction (IAM). The average ischemia time was 323 minutes, and the average door-to-needle time was 106 minutes. Fibrinolysis was successful in 67% of patients. Clinical factors associated with successful fibrinolysis were age (p=0.01), door-to-needle time (p=0.03), and ischemia time less than 120 minutes (p=0.04). According to ROC curves, cutoff points of 285 minutes for ischemia time and 70 minutes for door-to-needle time better predict fibrinolytic efficacy. Conclusions: Fibrinolytic efficacy was associated with age, ischemia time, and door-to-needle time. Furthermore, the identified cutoff points for these two times were 285 minutes and 70 minutes, respectively
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