Bibliographic citations
Vásquez, G., (2020). Hipernatremia como factor pronóstico de mortalidad en trauma encefalocraneano severo [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/6375
Vásquez, G., Hipernatremia como factor pronóstico de mortalidad en trauma encefalocraneano severo [Tesis]. : Universidad Privada Antenor Orrego - UPAO; 2020. https://hdl.handle.net/20.500.12759/6375
@mastersthesis{renati/380841,
title = "Hipernatremia como factor pronóstico de mortalidad en trauma encefalocraneano severo",
author = "Vásquez Tirado, Gustavo Adolfo",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2020"
}
INTRODUCTION: A severe traumatic brain injury is a frequent pathology, it implies a non-negligible morbidity and mortality. Hypernatremia could be considered a factor associated with poor prognosis in order to optimize treatment in the group of high-risk patients. OBJECTIVE: To determine if hypernatremia is a prognostic factor of mortality in patients with severe traumatic brain injury in a public hospital wich is a local reference center in trauma. MATERIAL AND METHOD: We performed a non-probabilistic sampling of adult patients of both sexes with severe traumatic brain injury from the Intensive Care Unit of the Hospital Regional Docente de Trujillo during the 2015–2018 period. RESULTS: Mortality in the group with and without hypernatremia was 38% and 6% respectively (p=0.001). The difference in natremia means values between the group with and without mortality was 21,86 (95% CI 18.2-25.5) (p=0.000). In the multivariate analysis, we found hypernatremia with adjusted OR of 16.73 (95% CI 1.96-142.82) (p=0.01). The ROC curve showed adequate performance to predict mortality, with an AUC 0.878 (95% CI 0.77-0.97) (p=0.00). CONCLUSION: Hypernatremia is a prognostic factor of mortality in patients with severe traumatic brain injury.
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