Citas bibligráficas
Palacios, E., (2023). Factores de riesgo para neumonía asociada a ventilador mecánico por Acinetobacter baumannii en pacientes adultos con COVID-19 crítico [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/10682
Palacios, E., Factores de riesgo para neumonía asociada a ventilador mecánico por Acinetobacter baumannii en pacientes adultos con COVID-19 crítico [Tesis]. PE: Universidad Privada Antenor Orrego; 2023. https://hdl.handle.net/20.500.12759/10682
@misc{renati/378731,
title = "Factores de riesgo para neumonía asociada a ventilador mecánico por Acinetobacter baumannii en pacientes adultos con COVID-19 crítico",
author = "Palacios Vásquez, Edwin Gerson",
publisher = "Universidad Privada Antenor Orrego",
year = "2023"
}
To identify the risk factors for ventilator-associated pneumonia (VAP) by Acinetobacter baumannii in adult patients with critical COVID-19 at the Hospital during the period January 2021 - March 2022. Methodology: Case-control study, which involved 106 cases with VAP due to Acinetobacter baumannii and 212 controls without A. baumannii infection, in whom age, sex, comorbidities, history of prior antibiotic therapy, time in intensive care unit (ICU), time on a mechanical ventilator, and serum albumin were risk factors. The odds ratio (OR) was calculated for the bivariate analysis and, with the significant variables, the multivariate analysis was performed by logistic regression. Results: The present study identified an association between age over 60 years (OR: 2.74, p<0.001) and mechanical ventilator-associated pneumonia. During the study, type 2 diabetes mellitus (OR: 2.55, 95%CI: 1.39-4.68, p=0.002), previous antibiotic therapy (OR: 1.91, 95%CI: 1.17- 3.18, p=0.008), severe hypoalbuminemia (OR: 24.42, 95%CI: 3.11-191.95, p<0.001) were found as risk factors. Arterial hypertension (p=0.333) and nephropathy (p=0.08) were not identified as risk factors. Likewise, it was found that Acinetobacter baumannii pneumonia significantly increased the length of hospital stay in ICU (31.2 ± 18.1 vs 23.1 ± 11.4, p<0.001) and time of mechanical ventilator use (28.4 ± 15.7 vs 15.7 ± 10.9, p<0.001). Multivariate analysis showed that age older than 60 years (OR: 2.89, 95%CI: 1.69-4.92), history of type 2 diabetes mellitus (OR: 2.33, 95%CI: 1.22-4.47), previous antibiotic therapy (OR: 2.13, 95%CI: 1. 25-3.64), hypoalbuminemia (OR: 2.19, 95%CI: 1.29-3.71) and severe hypoalbuminemia (OR: 17.34, 95%CI: 2.11-42.52), are independent risk factors for mechanical ventilator-associated pneumonia due to A. baumannii. Conclusions: Age, type 2 diabetes mellitus (T2DM), prior antibiotic therapy, and hypoalbuminemia are risk factors for VAP due to Acinetobacter baumannii in patients with critical COVID-19.
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