Citas bibligráficas
Cruz, H., (2018). Efectividad del índice PSA libre versus PSA total en el diagnóstico de cáncer de próstata [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/4288
Cruz, H., Efectividad del índice PSA libre versus PSA total en el diagnóstico de cáncer de próstata [Tesis]. : Universidad Privada Antenor Orrego - UPAO; 2018. https://hdl.handle.net/20.500.12759/4288
@misc{renati/376921,
title = "Efectividad del índice PSA libre versus PSA total en el diagnóstico de cáncer de próstata",
author = "Cruz Gutierrez, Henry Ray",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2018"
}
OBJECTIVE: To determine if the free PSA Index is more effective than the total PSA in the diagnosis of prostate cancer in patients with suspected prostate cancer who come to an outpatient clinic of urology of the Víctor Lazarte Echegaray Hospital in the period between January 2 014- January 2 018. MATERIAL AND METHODS: A study of diagnostic test was carried out; the selection process was carried out under inclusion and exclusion criteria, having 850 patients as a whole, but for purification reasons, only 190 were considered that were evaluated with our data collection sheet. RESULTS: Of the 190 patients, 99 had cancer and 91 did not present, the average age in years was 70.82+-5.9 and 64.75+-6.84 respectively. Statistically, a cut-off point was obtained for a free PSA Index of 0.16 with an area record under the ROC curve of 0.996; IC 95% and statistical significance (p<0.001); showing a sensitivity of 98.99%, specificity of 94.51%, positive predictive value of 95.15% and negative predictive value of 98.85%. Diagnostic accuracy was obtained for free PSA Index of 96.84% versus 54.21% of total PSA with a cut-off of 4 ng/ml. CONCLUSIONS: The free PSA Index test is more effective than total PSA in the diagnosis of prostate cancer, and at a cut-off 0.16, it detects the disease in 98.99%, and demonstrates an improvement in the specificity of total PSA to avoid unnecessary biopsies, especially when the values are in the gray area.
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