Citas bibligráficas
Huaman, M., (2021). Alteraciones de la gasometría arterial asociadas a retinopatía en prematuros de muy bajo peso al nacer [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/7774
Huaman, M., Alteraciones de la gasometría arterial asociadas a retinopatía en prematuros de muy bajo peso al nacer [Tesis]. PE: Universidad Privada Antenor Orrego - UPAO; 2021. https://hdl.handle.net/20.500.12759/7774
@mastersthesis{renati/374948,
title = "Alteraciones de la gasometría arterial asociadas a retinopatía en prematuros de muy bajo peso al nacer",
author = "Huaman Rodriguez, Martina Rosaria",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2021"
}
An observational, analytical, retrospective and longitudinal study was carried out, with a case-control design nested in a cohort, at the Hospital Belen de Trujillo, over a period of 5 years, with the objective of determining if the alterations in arterial blood gases were associated a retinopathy in very low birth weight premature infants. Two groups were identified: 49 cases and 147 controls. The association between each alteration of arterial blood gas and ROP was evaluated using the chi-square test of criteria independence and for the adjustment to the effect of the remaining alterations, the multivariate logistic regression analysis was performed. Hyperoxemia was present in 57.1% of these premature infants, with a statistically significant difference (p <0.05); however, hypoxemia, hypercapnia, and acidosis were present in a lower percentage (8.2%, 16.3%, and 18.4%, respectively). Gestational age <28 weeks, birth weight <1000 grams, cardiopulmonary resuscitation, orotracheal intubation, apgar <7 minutes after life, and the use of mechanical ventilation were associated with the presence of ROP with a statistically significant difference (p <0.05). Premature infants delivered via cesarean section presented ROP in a lower percentage than those delivered vaginally, with a statistically significant difference. In the multivariate analysis, it was observed that the only significant coefficient associated with ROP was gestational age <28 weeks with an odds ratio (OR = 7.34). Conclusions: Hyperoxemia in very low birth weight premature infants is associated with ROP; therefore, its presence in this age group increases the risk of ROP. Gestational age <28 weeks, weight <1000 grams, cardiopulmonary resuscitation, endotracheal intubation, mechanical ventilation, and apgar at 5 minutes <7 are associated with ROP; However, the only factor that significantly influences the estimation of ROP is gestational age <28 weeks, which increases the risk 7.34 times. Cesarean delivery reduces the risk of developing ROP.
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