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Rojas, P., (2024). Relación monocito-linfocito elevado como predictor de preeclampsia [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/35131
Rojas, P., Relación monocito-linfocito elevado como predictor de preeclampsia [Tesis]. PE: Universidad Privada Antenor Orrego; 2024. https://hdl.handle.net/20.500.12759/35131
@misc{renati/374098,
title = "Relación monocito-linfocito elevado como predictor de preeclampsia",
author = "Rojas Sánchez, Pedro Erasmo Junior",
publisher = "Universidad Privada Antenor Orrego",
year = "2024"
}
Título: Relación monocito-linfocito elevado como predictor de preeclampsia
Autor(es): Rojas Sánchez, Pedro Erasmo Junior
Asesor(es): Rodríguez Barboza, Héctor Uladismiro
Palabras clave: Relación Monocito-Linfocito; Predictor
Campo OCDE: https://purl.org/pe-repo/ocde/ford#3.02.27
Fecha de publicación: 2024
Institución: Universidad Privada Antenor Orrego
Resumen: Determinar si la relación monocito-linfocito elevada es predictor de
preeclampsia.
Material y métodos: entre enero 2021 a diciembre del 2023, en el Hospital
Albrecht de Trujillo, se llevó a cabo un estudio analítico, de casos y controles,
en el cual se incluyó a 168 historias clínicas de gestantes, 84 con preeclampsia
(casos), y 84 gestantes sin preeclampsia (controles). En las historias
seleccionadas, se verificó la existencia de un hemograma automatizado
realizado entre las 12 y 24 semanas de edad gestacional, para realizar el
cálculo de la relación monocito-linfocito (RML) y determinar si estaba elevada o
no. Se tomó como punto de corte para la RML elevada, el valor por encima de
0.325. Se utilizó el estadígrafo de Odds Ratio y chi cuadrado para
proporciones, con una confiabilidad del 95%.
Resultados: El 67,9% del grupo casos presentó la RML elevada, frente al
38,1% de control (p=0.01); con una media de RML de 0,33, en el grupo de
casos, frente al 0,29 del grupo control (p=0,01); el rendimiento de la RML como
predictor tuvo una sensibilidad de 67,86 % y una especificidad de 61,91%.
El análisis multivariado demostró que la nuliparidad, influye en el modelo de
predicción con un ORa = 2,32; IC 95% = 1,10 – 4,86; p = 0,04.
Conclusiones: La relación monocito-linfocito elevado, mostró ser útil como
predictor de preeclampsia en gestantes del hospital Albrecht del IPSS de
Trujillo.
To determine if an elevated monocyte-lymphocyte ratio is a predictor of preeclampsia. Materials and Methods: An analytical case-control study was conducted at the Albrecht Hospital in Trujillo from January 2021 to December 2023. A total of 168 medical records of pregnant women were included, consisting of 84 cases with preeclampsia and 84 controls without preeclampsia. The selected records were verified for the presence of an automated complete blood count performed between 12 and 24 weeks of gestational age to calculate the monocyte- lymphocyte ratio (MLR) and determine if it was elevated. A cutoff value above 0.325 was used to define an elevated MLR. Odds Ratio and chi-square tests for proportions were employed with a 95% confidence level. Results: In the case group, 67.9% exhibited an elevated MLR compared to 38.1% in the control group (p=0.01). The mean MLR was 0.33 in the case group and 0.29 in the control group (p=0.01). The MLR performance as a predictor showed a sensitivity of 67.86% and specificity of 61.91%. The multivariate analysis showed that nulliparity influences the prediction model with an ORa = 2.32; 95% CI = 1.10 – 4.86; p = 0.04 Conclusions: The elevated monocyte-lymphocyte ratio was shown to be useful as a predictor of preeclampsia in pregnant women at the Albrecht Hospital of the IPSS in Trujillo
To determine if an elevated monocyte-lymphocyte ratio is a predictor of preeclampsia. Materials and Methods: An analytical case-control study was conducted at the Albrecht Hospital in Trujillo from January 2021 to December 2023. A total of 168 medical records of pregnant women were included, consisting of 84 cases with preeclampsia and 84 controls without preeclampsia. The selected records were verified for the presence of an automated complete blood count performed between 12 and 24 weeks of gestational age to calculate the monocyte- lymphocyte ratio (MLR) and determine if it was elevated. A cutoff value above 0.325 was used to define an elevated MLR. Odds Ratio and chi-square tests for proportions were employed with a 95% confidence level. Results: In the case group, 67.9% exhibited an elevated MLR compared to 38.1% in the control group (p=0.01). The mean MLR was 0.33 in the case group and 0.29 in the control group (p=0.01). The MLR performance as a predictor showed a sensitivity of 67.86% and specificity of 61.91%. The multivariate analysis showed that nulliparity influences the prediction model with an ORa = 2.32; 95% CI = 1.10 – 4.86; p = 0.04 Conclusions: The elevated monocyte-lymphocyte ratio was shown to be useful as a predictor of preeclampsia in pregnant women at the Albrecht Hospital of the IPSS in Trujillo
Enlace al repositorio: https://hdl.handle.net/20.500.12759/35131
Disciplina académico-profesional: Medicina Humana
Institución que otorga el grado o título: Universidad Privada Antenor Orrego. Facultad de Medicina Humana
Grado o título: Medico Cirujano
Jurado: Vásquez Alvarado, Javier Ernesto; Salazar Cruzado Orlando Rodolfo; Urteaga Vargas, Patricia
Fecha de registro: 30-jul-2024
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