Bibliographic citations
Silva, M., (2024). Efectividad del Índice de Inmunidad-Inflamación Sistémica como predictor de apendicitis aguda complicada [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/35211
Silva, M., Efectividad del Índice de Inmunidad-Inflamación Sistémica como predictor de apendicitis aguda complicada [Tesis]. PE: Universidad Privada Antenor Orrego; 2024. https://hdl.handle.net/20.500.12759/35211
@misc{renati/373870,
title = "Efectividad del Índice de Inmunidad-Inflamación Sistémica como predictor de apendicitis aguda complicada",
author = "Silva Goycochea, Milagros Stefany",
publisher = "Universidad Privada Antenor Orrego",
year = "2024"
}
determine if the Systemic Immunity-Inflammation Index is more effective than the Neutrophil Lymphocyte Ratio, C-Reactive Protein and Leukocyte Count as a predictor of complicated acute appendicitis in appendectomized patients. Materials and methods: A study of diagnostic tests was developed that included 261 patients with a diagnosis of acute appendicitis treated at the Trujillo Regional Teaching Hospital during the period 2022 - 2023. These were divided into two groups based on the anatomo-pathological report; in group I: patients with complicated acute appendicitis, and group II: patients with uncomplicated acute appendicitis, to finally calculate the Systemic Immunity-Inflammation Index, the Neutrophil Lymphocyte Ratio, the C-Reactive Protein and the Leukocyte Count in both groups. The ROC curve technique was used to find the area under the curve that allowed identifying the optimal cut-off points to finally calculate the indicators of sensitivity, specificity, positive predictive value and negative predictive value for each test. Results: The median age for the group with acute uncomplicated appendicitis was 34 (25 49), while in the group with acute complicated appendicitis a significantly higher median age of 43 (27 53) was obtained. The proportion of men in the group with complicated acute appendicitis was 36.8% and in the uncomplicated group, 17.2%. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy values of the Systemic Immunity-Inflammation Index were (76%, 94%, 94%, 71% and 84%), the Neutrophil Lymphocyte Ratio was (76%, 94%, 94%, 71% and 81%), the C-Reactive Protein was (86%, 82%, 88%, 79% and 88%) and the Leukocyte Count was (66%, 80 %, 84%, 59% and 76%) respectively. Conclusion: The Systemic Immunity-Inflammation Index has greater validity to predict complicated acute appendicitis compared to the Neutrophil Lymphocyte Ratio and the Leukocyte Count; However, its validity is lower than C-Reactive Protein. The latter is the best predictor of complicated acute appendicitis according to the results obtained in the present investigation.
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