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Holguín, G., (2019). Obesidad como factor de riesgo para psoriasis en pacientes adultos [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/5286
Holguín, G., Obesidad como factor de riesgo para psoriasis en pacientes adultos [Tesis]. : Universidad Privada Antenor Orrego - UPAO; 2019. https://hdl.handle.net/20.500.12759/5286
@misc{renati/373088,
title = "Obesidad como factor de riesgo para psoriasis en pacientes adultos",
author = "Holguín Reyes, Grecia Mabel",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2019"
}
Title: Obesidad como factor de riesgo para psoriasis en pacientes adultos
Authors(s): Holguín Reyes, Grecia Mabel
Advisor(s): Chira Romero, Flor Elena
Keywords: Obesidad; Psoriasis; Dislipidemia; Diabetes mellitus
Issue Date: 2019
Institution: Universidad Privada Antenor Orrego - UPAO
Abstract: Objetivo: Determinar la relación entre la obesidad y la psoriasis en pacientes adultos.
Materiales y métodos: Se realizó un estudio analítico, longitudinal, retrospectivo y de casos y controles, en donde se incluyeron 264 pacientes adultos que pasaron por consultorios externos de Dermatología del Hospital Víctor Lazarte Echegaray durante el periodo 2014 – 2018. Se utilizó análisis bivariado usando prueba Chi Cuadrado de Pearson con un nivel de significancia del 5% (p < 0,05), con la medida de riesgo del Odds ratio con su respectivo intervalo de confianza del 95%. Para el análisis multivariado se utilizó la regresión logística múltiple con Odds ratios ajustados con sus respectivos intervalos de confianza al 95%.
Resultados: Se incluyeron 264 pacientes, 88 casos y 176 controles. La obesidad fue identificada en el 31.8% de los casos frente al 11.9% de los controles, diferencia que fue estadísticamente significativa (p: 0.0001; OR: 3.44; IC95%: 1,82-6,53). El tipo de psoriasis más frecuente fue el de placas (90.9%); en cuanto a las comorbilidades (dislipidemia, diabetes mellitus e hipertensión arterial) se encontró que sólo la dislipidemia se asocia significativamente a psoriasis en un 68.2% (p: 0,017); en cuanto a la edad no se encontró asociación significativa con la psoriasis, sin embargo, el sexo masculino se encontró en un 55.7% en pacientes con psoriasis frente a un 28.4% en pacientes sin psoriasis (p:0.0001). Los OR ajustados para la obesidad fue de 3.37 con IC95%: 1.707-6.651; para la dislipidemia fue de 2.31 con un IC95%: 1.288-4.144; para el sexo masculino fue de 3.42 con un IC95%: 1.943-6.044.
Conclusiones: La obesidad es un factor de riesgo para la psoriasis en pacientes adultos, siendo esta asociación estadísticamente significativa.
Objective: Determine the relationship between obesity and psoriasis in adult patients. Methodology and material: An study analytical, longitudinal, retrospective, and case – control study as carried out, where 264 adult patients were included who went through outpatient clinics of Dermatology of the Hospital Victor Lazarte Echegaray during the period 2014 – 2018. Bivariate analysis was used using Chi Square test Pearson with a level of significance of 5%( p < 0,05), with the risk measure of the Odds ratio with its respective 95% confidence interval. For the multivariate analysis, multiple logistic regression with Odds ratios adjusted with their respective 95% confidence intervals was used. Results: 264 patients were included, 88 cases and 176 controls. Obesity was identified in 31.8% of the cases compared to 11.9% of the controls, a difference that was statistically significant (p: 0.0001, OR: 3.44, 95%IC: 1.82-6.53). The most frequent type of psoriasis was plaque (90.9%); regarding comorbidities (dyslipidemia, diabetes mellitus and arterial hypertension), it was found that only dyslipidemia is significantly associated with psoriasis in 68.2% (p:0.017); regarding age, no association was found psoriasis, however, the male sex was found in 55.7% of patients with psoriasis compared to 28.4% in patients without psoriasis (p:0.0001). The OR adjusted for obesity was 3.37 with 95% CI: 1,707-6,651; for dyslipidemia it was 2.31 with an IC95%: 1.288-4.144; for the male sex it was 3.42 with an IC95%: 1.943-6.044. The OR adjusted for obesity was 3.37 with 95% CI: 1,707-6,651; for dyslipidemia it was 2.31 with an IC95%: 1.288-4.144; for the male sex it was 3.42 with an IC95%: 1.943-6.044. Conclusions: Obesity is a risk factor for psoriasis in adult patients, this association being statistically significant.
Objective: Determine the relationship between obesity and psoriasis in adult patients. Methodology and material: An study analytical, longitudinal, retrospective, and case – control study as carried out, where 264 adult patients were included who went through outpatient clinics of Dermatology of the Hospital Victor Lazarte Echegaray during the period 2014 – 2018. Bivariate analysis was used using Chi Square test Pearson with a level of significance of 5%( p < 0,05), with the risk measure of the Odds ratio with its respective 95% confidence interval. For the multivariate analysis, multiple logistic regression with Odds ratios adjusted with their respective 95% confidence intervals was used. Results: 264 patients were included, 88 cases and 176 controls. Obesity was identified in 31.8% of the cases compared to 11.9% of the controls, a difference that was statistically significant (p: 0.0001, OR: 3.44, 95%IC: 1.82-6.53). The most frequent type of psoriasis was plaque (90.9%); regarding comorbidities (dyslipidemia, diabetes mellitus and arterial hypertension), it was found that only dyslipidemia is significantly associated with psoriasis in 68.2% (p:0.017); regarding age, no association was found psoriasis, however, the male sex was found in 55.7% of patients with psoriasis compared to 28.4% in patients without psoriasis (p:0.0001). The OR adjusted for obesity was 3.37 with 95% CI: 1,707-6,651; for dyslipidemia it was 2.31 with an IC95%: 1.288-4.144; for the male sex it was 3.42 with an IC95%: 1.943-6.044. The OR adjusted for obesity was 3.37 with 95% CI: 1,707-6,651; for dyslipidemia it was 2.31 with an IC95%: 1.288-4.144; for the male sex it was 3.42 with an IC95%: 1.943-6.044. Conclusions: Obesity is a risk factor for psoriasis in adult patients, this association being statistically significant.
Link to repository: https://hdl.handle.net/20.500.12759/5286
Discipline: Medicina Humana
Grade or title grantor: Universidad Privada Antenor Orrego. Facultad de Medicina Humana
Grade or title: Médico Cirujano
Register date: 13-Aug-2019
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