Citas bibligráficas
Neyra, L., Armas, N. (2018). Evaluación in vitro de la actividad fungicida y fungistática del extracto metanólico de la minthostachys mollis (muña) sobre cepa de candida albicans ATCC®1023 [Tesis, Universidad Peruana de Ciencias Aplicadas (UPC)]. http://hdl.handle.net/10757/625175
Neyra, L., Armas, N. Evaluación in vitro de la actividad fungicida y fungistática del extracto metanólico de la minthostachys mollis (muña) sobre cepa de candida albicans ATCC®1023 [Tesis]. PE: Universidad Peruana de Ciencias Aplicadas (UPC); 2018. http://hdl.handle.net/10757/625175
@misc{renati/367847,
title = "Evaluación in vitro de la actividad fungicida y fungistática del extracto metanólico de la minthostachys mollis (muña) sobre cepa de candida albicans ATCC®1023",
author = "Armas Gálvez, Nelson Mauricio",
publisher = "Universidad Peruana de Ciencias Aplicadas (UPC)",
year = "2018"
}
Objective: to evaluate in vitro the fungistatic and fungicidal activity of the methanolic extract of Minthostachys Mollis (Muña) on strains of Candida albicans. Methods: Three in vitro methanolic extracts of the leaves, stems and roots of Minthostachys mollis were made. The fungistatic activity of the extracts against Candida albicans strains was evaluated by means of the agar diffusion technique. Minimun inhibitory concentration (MIC) was determined by the microdilution method and cytotoxicity using the MDCK cell line. Results: The extracts that obtained the greatest fungistatic activity at 24 hours were those of leaves and stems against Candida albicans, halos of 47.72 ± 6.67mm and 46.58 ± 6.42mm respectively were obtained, finding no statistically significant difference. The MIC for leaves was 46.87mg / ml, for stems was 93.75mg / ml and 1500mg / ml for roots. Conclusions: It was demonstrated that the methanolic extracts of Minthostachys mollis have fungistatic and fungicidal activity against strains of Candida albicans. None of the extracts turned out to be toxic on cell lines at low concentrations.
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