Citas bibligráficas
Champi, G., Lara, F. (2024). Volumen plaquetario medio (VPM) y el índice plaquetas/linfocitos (IPL) como predictor de severidad en preeclampsia del Hospital Regional del Cusco en el periodo 2020 – 2023. [Universidad Andina del Cusco]. https://hdl.handle.net/20.500.12557/6562
Champi, G., Lara, F. Volumen plaquetario medio (VPM) y el índice plaquetas/linfocitos (IPL) como predictor de severidad en preeclampsia del Hospital Regional del Cusco en el periodo 2020 – 2023. []. PE: Universidad Andina del Cusco; 2024. https://hdl.handle.net/20.500.12557/6562
@misc{renati/24187,
title = "Volumen plaquetario medio (VPM) y el índice plaquetas/linfocitos (IPL) como predictor de severidad en preeclampsia del Hospital Regional del Cusco en el periodo 2020 – 2023.",
author = "Lara Velasque, Fiorela",
publisher = "Universidad Andina del Cusco",
year = "2024"
}
Objective: To identify whether Mean Platelet Volume (MPV) and Platelet/Lymphocyte Ratio (PLR) serve aspredictors of preeclampsia severity at the Regional Hospital of Cusco during the period 2020 – 2023. Materials and Methods: A non-experimental, analytical, case-control, cross-sectional, retrospective, and quantitative study using data from clinical records. The population included 158 patients classified as cases (PE with severity criteria) and controls (PE without severity criteria). Tests such as Mann-Whitney U and chi-square were applied to examine the relationship with the severity of preeclampsia. A logistic regression model was developed with significant predictive markers, and its accuracy was evaluated using sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). The model's ability to distinguish between cases of severe and non-severe preeclampsia was assessed using ROC and AUC, identifying an optimal point with the Youden test. Results: The Mean Platelet Volume (MPV) as an indicator reveals an Area under the Curve (AUC) of 0.6259 (95% CI: 0.57 – 0.74). The optimal cutoff point for MPV was established at ≥ 9.5 to identify cases of severe preeclampsia, with a sensitivity of 42.86% and a specificity of 78.33%. The Positive Predictive Value (PPV) was 76.36%, and the Negative Predictive Value (NPV) was 45.63%, showing no significance. Regarding the Platelet/Lymphocyte Ratio (PLR) as an indicator, an Area under the Curve (AUC) of 0.7112 (95% CI: 0.62-0.79) was found. A PLR value < 115.493 is considered positive for preeclampsia with severity criteria, with a sensitivity of 69.57% and a specificity of 65.15%. The Positive Predictive Value (PPV) was 73.56%, and the Negative Predictive Value (NPV) was 60.56%, being statistically significant. Conclusions: The Platelet/Lymphocyte Ratio (PLR) identified statistically significant differences, indicating its potential utility in predicting the severity of this disease.
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