Citas bibligráficas
Ayala, A., (2025). Hipercolesterolemia asociado a neuropatía en pacientes con diabetes mellitus tipo 2 en Hospital III José Cayetano Heredia – Piura [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/58471
Ayala, A., Hipercolesterolemia asociado a neuropatía en pacientes con diabetes mellitus tipo 2 en Hospital III José Cayetano Heredia – Piura [Tesis]. PE: Universidad Privada Antenor Orrego; 2025. https://hdl.handle.net/20.500.12759/58471
@misc{renati/1741831,
title = "Hipercolesterolemia asociado a neuropatía en pacientes con diabetes mellitus tipo 2 en Hospital III José Cayetano Heredia – Piura",
author = "Ayala Talledo, Aldair Frank",
publisher = "Universidad Privada Antenor Orrego",
year = "2025"
}
To determine the association between the presence of hypercholesterolemia and neuropathy in patients with type 2 diabetes mellitus treated at Hospital III José Cayetano Heredia in Piura. Materials and Methods: A retrospective cohort study design was employed, analyzing a total of 168 patients diagnosed with type 2 diabetes mellitus. The patients were divided into two groups: 56 who developed neuropathy (exposed group) and 112 who did not (non-exposed group). Information on clinical variables, including hypercholesterolemia, hypertension, obesity, and disease duration, was obtained through the review of medical records. The collected data were statistically analyzed using tests such as Pearson's Chi-square to evaluate the relationship between neuropathy and the studied variables, aiming to identify factors that might be associated with the development of this complication in diabetic patients. The analysis focused on understanding how these variables contribute to the onset of neuropathy in this specific patient population, which is crucial for establishing more effective prevention and management strategies. Results: In this study, it was found that 73.21% of patients with neuropathy had hypercholesterolemia, compared to 55.36% of patients without neuropathy, showing a statistically significant association (p = 0.025). No significant relationship was observed between hypertension or sex and neuropathy. However, obesity was present in 69.64% of patients with neuropathy compared to 50.89% in patients without the condition, indicating a significant association (p = 0.021). Additionally, a longer disease duration (≥ 5 years) was also significantly associated with the presence of neuropathy (p = 0.049). Conclusions: The results of this study conclude that hypercholesterolemia and obesity are significantly associated with the presence of neuropathy in patients with type 2 diabetes mellitus, highlighting the importance of addressing these factors in the prevention and management of neuropathy. No significant association was found between hypertension or sex and neuropathy, suggesting that these factors may not be determinants in the development of this complication. Furthermore, it was observed that a longer disease duration is also associated with a higher likelihood of neuropathy, emphasizing the need for rigorous long-term diabetes control, with a particular focus on cholesterol management and weight control to mitigate the risk of neuropathic complications in this vulnerable population.
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