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Estrada, J., (2020). Insulinoresistencia como factor asociado a la severidad del acné inflamatorio [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/6178
Estrada, J., Insulinoresistencia como factor asociado a la severidad del acné inflamatorio [Tesis]. PE: Universidad Privada Antenor Orrego; 2020. https://hdl.handle.net/20.500.12759/6178
@misc{renati/1343685,
title = "Insulinoresistencia como factor asociado a la severidad del acné inflamatorio",
author = "Estrada Florián, Jazmín Jasell",
publisher = "Universidad Privada Antenor Orrego",
year = "2020"
}
Título: Insulinoresistencia como factor asociado a la severidad del acné inflamatorio
Autor(es): Estrada Florián, Jazmín Jasell
Asesor(es): Ibáñez Relúz, Miguel Ángel
Palabras clave: Insulinoresistencia; Acné inflamatorio; HOMA-IR; Severidad
Campo OCDE: https://purl.org/pe-repo/ocde/ford#3.02.27
Fecha de publicación: 2020
Institución: Universidad Privada Antenor Orrego
Resumen: Objetivo: Determinar si la insulinoresistencia es un factor asociado a la severidad del acné
inflamatorio en pacientes atendidos en el consultorio externo del servicio de dermatología
del hospital de especialidades básicas la Noria.
Material y métodos: Se ejecutó el siguiente estudio analítico, observacional, prospectivo,
transversal constituiada por una población de 68 pacientes con acné inflamatorio leve a
moderado y severo atendidos en el consultorio de dermatología del Hospital de
Especialidades Básicas La Noria; de los cuales se analizó los niveles séricos de glucosa
basal e insulina basal en ayunas; mediante el índice de Homeostasis Model Assessment
(HOMA-IR) para cada individuo, obteniéndose como resultado pacientes con
insulinoresistencia y sin insulinoresistencia.
Se utilizaron pruebas como T student para comparar medias y Chi cuadrado para comparar
proporciones. La significancia estadística se consideró significativa si la posibilidad de
equivocarse es menor al 5% (p <0.05).
Resultados: Se analizaron un total de 68 pacientes en este estudio. La prevalencia de
insulinoresistencia en los pacientes con acné inflamatorio severo fue del 57, 69%. La
prevalencia de insulinoresistencia en pacientes con acné inflamatorio leve a moderado fue
de 30.95 %.
Se encontró asociación estadísticamente significativa entre las variables en mención y se
mostró que los pacientes con insulinoresistencia tienen 3.04 mayor riesgo de padecer acné
inflamatorio severo (p=0.029; ORP 3.04; 1.10-8.41). Con respecto a las variables
intervinientes como la edad, el peso, la talla, el IMC, el sexo, la historia familiar de acné
infamatorio, el estrés, la exposición solar, el consumo de tabaco, no se halló significancia
estadística por lo que se determina que dichas variables no modifican el efecto de la
insulinoresistencia en la severidad del acné. (p > 0. 05)
Conclusiones: La insulinoresistencia es un factor asociado a la severidad del acné
inflamatorio.
Objective: To determine if insulin resistance is a factor associated with the severity of inflammatory-acne in patients treated in the external office of the dermatology service of the basic specialty hospital La Noria. Material and methods: The following analytical, observational, prospective, cross-sectional study was carried out, consisting of a population of 68 patients with mild to moderate and severe inflammatory acne treated at the dermatology clinic of the Hospital de Especialidades Básicas La Noria; of which the serum levels of fasting basal glucose and basal insulin were analyzed; by means of the Homeostasis Model Assessment index (HOMA-IR) for each individual, obtaining as a result patients with insulin resistance and without insulin resistance. Tests such as T student were used to compare means and Chi square to compare proportions. Statistical significance was considered significant if the possibility of being wrong is less than 5% (p <0.05). Results: A total of 68 patients were analyzed in this study. The prevalence of insulin resistance in patients with severe inflammatory acne was 57, 69%. The prevalence of insulin resistance in patients with mild to moderate inflammatory acne was 30.95%. A statistically significant association was found between the variables mentioned and it was shown that patients with insulin resistance have a 3.04 higher risk of suffering from severe inflammatory acne (p = 0.029; ORP 3.04; 1.10-8.41). Regarding the intervening variables such as age, weight, height, BMI, sex, family history of inflammatory acne, stress, sun exposure, and smoking, there was no statistical significance for what it determines that these variables do not modify the effect of insulin resistance on the severity of acne (p> 0. 05). Conclusions: Insulin resistance is a factor associated with the severity of inflammatory acne.
Objective: To determine if insulin resistance is a factor associated with the severity of inflammatory-acne in patients treated in the external office of the dermatology service of the basic specialty hospital La Noria. Material and methods: The following analytical, observational, prospective, cross-sectional study was carried out, consisting of a population of 68 patients with mild to moderate and severe inflammatory acne treated at the dermatology clinic of the Hospital de Especialidades Básicas La Noria; of which the serum levels of fasting basal glucose and basal insulin were analyzed; by means of the Homeostasis Model Assessment index (HOMA-IR) for each individual, obtaining as a result patients with insulin resistance and without insulin resistance. Tests such as T student were used to compare means and Chi square to compare proportions. Statistical significance was considered significant if the possibility of being wrong is less than 5% (p <0.05). Results: A total of 68 patients were analyzed in this study. The prevalence of insulin resistance in patients with severe inflammatory acne was 57, 69%. The prevalence of insulin resistance in patients with mild to moderate inflammatory acne was 30.95%. A statistically significant association was found between the variables mentioned and it was shown that patients with insulin resistance have a 3.04 higher risk of suffering from severe inflammatory acne (p = 0.029; ORP 3.04; 1.10-8.41). Regarding the intervening variables such as age, weight, height, BMI, sex, family history of inflammatory acne, stress, sun exposure, and smoking, there was no statistical significance for what it determines that these variables do not modify the effect of insulin resistance on the severity of acne (p> 0. 05). Conclusions: Insulin resistance is a factor associated with the severity of inflammatory acne.
Enlace al repositorio: https://hdl.handle.net/20.500.12759/6178
Disciplina académico-profesional: Medicina Humana
Institución que otorga el grado o título: Universidad Privada Antenor Orrego. Facultad de Medicina Humana
Grado o título: Médico Cirujano
Fecha de registro: 9-may-2020
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