Citas bibligráficas
Antay, R., Castillo, C., Guevara, G. (2024). Altura elevada como factor de riesgo para hipertensión pulmonar en pacientes con cardiopatías congénitas: un estudio de casos y controles [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/16529
Antay, R., Castillo, C., Guevara, G. Altura elevada como factor de riesgo para hipertensión pulmonar en pacientes con cardiopatías congénitas: un estudio de casos y controles []. PE: Universidad Peruana Cayetano Heredia; 2024. https://hdl.handle.net/20.500.12866/16529
@misc{renati/1060332,
title = "Altura elevada como factor de riesgo para hipertensión pulmonar en pacientes con cardiopatías congénitas: un estudio de casos y controles",
author = "Guevara Arriaga, Gabriela",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2024"
}
Introduction: Congenital heart disease is a prevalent disease in pediatric age and the congenital malformation with the highest mortality. A higher prevalence of congenital heart disease has been seen in high altitude areas in Peru. Pulmonary hypertension (PH) is frequent in patients with congenital heart disease and its prevalence increases depending on the altitude at which the patient lives according to Chen et al. Patients with PH living at high altitude would not be able to access treatment and are more likely to die. Objective: To identify whether coming from a high altitude locality is a risk factor for developing pulmonary hypertension in patients with congenital heart disease in the pediatric cardiology service of INCOR between 2010 and 2019. Materials and Methods: We will perform a case-control study. After requesting the respective permissions, a database of patients seen between 2010 and 2019 will be made using EsSalud electronic records. Diagnoses will be expressed in frequency and according to ICD-11 nomenclature. Patients with intermediate-high probability of pulmonary hypertension will be selected by echocardiography and a sample of 1628 patients will be taken, then controls will be matched according to age and similar diagnoses. Epidemiological characteristics will be expressed in tables and graphics. A comparative analysis by logistic regression will be performed between the study variables (height and probability of pulmonary hypertension) and certain covariates (age, presence of syndromes, presence of pulmonary hyperflow and surgical or catheterization intervention) to obtain an adjusted odds ratio. Conclusion: PH in patients with congenital heart disease is a frequent complication and is associated with high altitude, thus requiring a higher level of evidence study to generalize such findings.
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