Bibliographic citations
Salinas, S., Cabello, A. (2023). Características clínicas, bioquímicas y radiológicas en niñas con pubertad precoz central atendidas en un hospital público de Lima 2014-2019 [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/13428
Salinas, S., Cabello, A. Características clínicas, bioquímicas y radiológicas en niñas con pubertad precoz central atendidas en un hospital público de Lima 2014-2019 []. PE: Universidad Peruana Cayetano Heredia; 2023. https://hdl.handle.net/20.500.12866/13428
@misc{sunedu/3384911,
title = "Características clínicas, bioquímicas y radiológicas en niñas con pubertad precoz central atendidas en un hospital público de Lima 2014-2019",
author = "Cabello Sanchez, Almendra Celeste",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2023"
}
Background: The diagnosis of central precocious puberty (CPP) in girls is frequent, being late affects the final adult height. Objective: To describe the clinical, biochemical and radiological characteristics in girls with CPP attended in a public hospital in Lima between 2014-2019. Materials and methods: Case series. Clinical histories of girls with a diagnosis of CPP were reviewed.PPP, isolated thelarche and malformations were excluded.Z-IMC, genetic Z-height, Z-height and PFTA were calculated. T-Student, t-test, Wilcoxon and Shapiro-Wilk were used by STATA software 17 version. P<0,05 was considered statistically significant. The study was approved by the ICD of UPCH and HCH. Results: 86 histories were reviewed. Mean chronological age was 8,16±1,09SD and mean bone age was 10,33±1,27SD. Statistically significant differences (P=0,000) were found between the means of bone age and chronological age, the Z-height of the girl and the genetic Z-height as well as PTFA and TG. M2(19,7%), M3(59,3%), M4(20,9%), normal weight(27,9%), overweight (30,2%) and obesity(41,8%) were found. The median LH was 0,6(RIQ:0,4-1,8) and FSH, 3,4(RIQ:2,1-5,2) Conclusions: The chronological age at diagnosis was late with a significantly higher bone age than chronological. The height relative of girls regarding her TG was significantly higher. PTFA was significantly lower than TG. Most of them presented advanced breast development, overweight and obesity. It is necessary to train and sensitize physicians for earlier suspicion and referral.
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