Factores de riesgo de injuria renal aguda en pacientes hospitalizados con Covid 19 en el Hospital Nacional Adolfo Guevara Velasco – Essalud Cusco. periodo marzo 2020 – 2022.

Abstract

Introducción: A fines de 2019, surgió un nuevo coronavirus, este desató una pandemia mundial, el virus daña las células del riñón, las tubulares y los podocitos, lo que provoca lesión renal aguda. 3 Objetivo: Identificar los factores de riesgo de Injuria Renal Aguda en pacientes hospitalizados con COVID 19 en el Hospital Nacional Adolfo Guevara Velasco. Periodo Marzo 2020 – 2022. Materiales y método: Es un estudio analítico de casos y controles. Se utilizó ficha de recolección de datos de las historias clínicas de 250 pacientes hospitalizados con COVID 19 en el Hospital Nacional Adolfo Guevara Velasco, 125 casos y 125 controles. Consideramos casos a los pacientes con el diagnóstico de Injuria Renal Aguda y controles a los pacientes sin Injuria Renal Aguda. Se realizó un análisis univariado y bivariado. Resultados: Los factores de riesgo fueron: sepsis (P= 0.000, OR= 14.40 [Li=6.48; Ls=31.95]), estancias más de 30 días (P= 0.000, OR= 13.94 [Li= 6.28; Ls=30.95]), inmunosupresores (P=0.006; OR= 10.78 [Li= 1.36; Ls=85.56]), vasopresores (P= 0.000, OR= 4.70 [Li= 2.49; Ls= 8.86]), obesidad (P= 0.00; OR= 4.87 [Li= 2.54; Ls= 9.33]), ERC (P= 0.000, OR= 6.46 [Li= 2.16; Ls=19.36], hipertensión Arterial (P= 0.000, OR= 3.43 [Li= 1.99; Ls= 5.89]) y ventilación mecánica (P= 0.001, OR= 2.37 [Li= 1.40; Ls= 4.01]). Conclusiones: El principal factor de riesgo en este estudio fue sepsis. Seguido de estancia hospitalaria > 30 días, inmunosupresores, vasopresores, obesidad, ERC, HTA.

Introduction: At the end of At the end of 2019, a new coronavirus emerged, it spread rapidly and became a global pandemic, the virus damages kidney cells, such as tubular cells and podocytes, what causes acute kidney injury.3 Objective: Identify the risk factors for Acute Kidney Injury in patients hospitalized with COVID 19 at the Adolfo Guevara Velasco National Hospital - ESSALUD Cusco. Period March 2020 – 2022. Materials and method: It is an analytical study of cases and controls. A data collection sheet was used from the medical records of 250 patients hospitalized with COVID 19 at the Adolfo Guevara Velasco National Hospital, 125 cases and 125 controls. We considered patients with the diagnosis of Acute Kidney Injury as cases and patients without Acute Kidney Injury as controls. A univariate and bivariate analysis was performed. Results: The risk factors were sepsis (P= 0.000, OR= 14.40 [Li= 6.48; Ls= 31.95, stays longer than 30 days (P= 0.000, OR= 13.94 [Li= 6.28; Ls= 30.95]), Inmunosupppressive (P=0.006; OR= 10.78 [Li= 1.36; Ls=85.56]), vasopressors (P= 0.000, OR= 4.70 [Li= 2.49; Ls= 8.86]), obesity (P= 0.00; OR= 4.87 [Li= 2.54; Ls= 9.33]), CKD (P= 0.000, OR= 6.46 [Li= 2.16; Ls=19.36], Arterial Hypertension (P= 0.000, OR= 3.43 [Li= 1.99; Ls= 5.89]), mechanical ventilation (P= 0.001, OR= 2.37 [Li= 1.40; Ls= 4.01]) y diabetes (P=0.000; OR=1.68 [Li= 1.34; Ls= 2.11]). Conclusions: The main risk factors was sepsis. Followed by prolonged hospital stay, obesity, diabetes mellitus, arterial hypertension, mechanical ventilation,