Bibliographic citations
Sanchez, J., (2022). Estudio comparativo de las características histopatológicas del fibroma osificante y la displasia fibrosa de los maxilares en el Centro Dental Docente de la Universidad Peruana Cayetano Heredia, Lima-Perú [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/14329
Sanchez, J., Estudio comparativo de las características histopatológicas del fibroma osificante y la displasia fibrosa de los maxilares en el Centro Dental Docente de la Universidad Peruana Cayetano Heredia, Lima-Perú []. PE: Universidad Peruana Cayetano Heredia; 2022. https://hdl.handle.net/20.500.12866/14329
@mastersthesis{renati/910893,
title = "Estudio comparativo de las características histopatológicas del fibroma osificante y la displasia fibrosa de los maxilares en el Centro Dental Docente de la Universidad Peruana Cayetano Heredia, Lima-Perú",
author = "Sanchez Leon, Jairo",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2022"
}
Introduction: The classification of fibro-osseous lesions in the jaws according to the WHO (2017) includes ossifying fibroma (OF) and fibrous dysplasia (FD); histopathology is decisive for its diagnosis and treatment. Objective: To evaluate the main histopathological characteristics for the diagnosis of both lesions in the jaws, according to sex, age, histopathology of the bone and/or stroma. Material and method: The study was analytical, descriptive, cross-sectional and retrospective; the sample was based on records and histopathological slides of the Teaching Dental Center-UPCH, excluding cases with an associated syndrome. Results: There was a predilection for female sex in both lesions, and the most frequent location of OF was the posterior region of mandible and for FD was the posterior region of maxilla; histopathology showed mature bone in almost all cases of OF (p<0.001). Immature bone was present in all FD lesions, while in OF only 49.09% (p<0.001). The stroma was mostly fibrocellular in both lesions, the shape of the fibroblast nuclei was round in 74.55% of the OF (p<0.033). The fibrous capsule was present in some cases of OF, and absent in FD (p<0.007). Conclusion: OF is the most frequent fibro-osseous lesion; In all cases of FD there was immature bone, peritrabecular fissure, distribution of irregular type collagen fibers, absence of fibrous capsule and absence of mitotic figures. Most OF cases presented a 2:1 soft-to-hard tissue ratio, irregular bone morphology, and rounded fibroblast nuclei.
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