Bibliographic citations
Palomino, N., Vegas, A. (2023). Perfil epidemiológico de la intoxicación por metanol en un hospital nivel III-1 de Lima, Perú desde septiembre hasta noviembre de 2022 [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/14022
Palomino, N., Vegas, A. Perfil epidemiológico de la intoxicación por metanol en un hospital nivel III-1 de Lima, Perú desde septiembre hasta noviembre de 2022 []. PE: Universidad Peruana Cayetano Heredia; 2023. https://hdl.handle.net/20.500.12866/14022
@misc{renati/910854,
title = "Perfil epidemiológico de la intoxicación por metanol en un hospital nivel III-1 de Lima, Perú desde septiembre hasta noviembre de 2022",
author = "Vegas Aguirre, Alexandra Jimena",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2023"
}
Background: Methanol intoxication has exhibited limited occurrences in Peru historically with reported annual cases of acute intoxication ranging from 1-4. However, during the period from September to November 2022, there was a notable increase in cases at the north of Lima. Objectives: To describe the demographic, clinical and laboratory characteristics, as well as prognostic factors, of patients with methanol poisoning who sought emergency care at Cayetano Heredia Hospital between September and November 2022. Materials and Methods: This is a longitudinal and retrospective case series study of exploratory nature with non probabilistic and convenience sampling methods. Results: A total of 38 medical records were reviewed. 32 patients (84,21%) were male, (50%) reported having consumed a beverage called “Punto D Oro”. The most frequently reported symptoms were nausea and vomiting in 28 cases (73,68%) and decreased visual acuity in 20 cases (52,63%). The median pH was 6,85 (IQR:0,43), and the mean anion gap was 39,02 (SD:39,02). The median creatinine was 1,35 (IQR:0,95). In the bivariate analysis, the variables associated with mortality were elevated anion gap (>12) (OR: 1.286 [1,05 – 1.339]; p 0,001), elevated creatinine levels (>1.3 mg/dL) (OR: 3,738 [1,084 – 12,885]; p 0,037), ECG ≤ 8 points (OR: 12 [2,34 – 61,449]; p 0,003), MAP ≤ 80 mmHg (OR: 8,556 [1,682 – 43,495]; p 0,010), and serum bicarbonate ≤ 6 mmol/L (OR: 14,143 [2,479 – 80,682]; p 0,003]. Conclusion: The only variable independently related to mortality was the elevated anion gap (>12).
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