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Chacon, E., (2017). Asociaciones antibióticas usos e indicaciones en odontología [Trabajo de suficiencia profesional, Universidad Inca Garcilaso de la Vega]. https://hdl.handle.net/20.500.11818/1335
Chacon, E., Asociaciones antibióticas usos e indicaciones en odontología [Trabajo de suficiencia profesional]. : Universidad Inca Garcilaso de la Vega; 2017. https://hdl.handle.net/20.500.11818/1335
@misc{renati/860803,
title = "Asociaciones antibióticas usos e indicaciones en odontología",
author = "Chacon Hernandez, Eyleen",
publisher = "Universidad Inca Garcilaso de la Vega",
year = "2017"
}
Title: Asociaciones antibióticas usos e indicaciones en odontología
Authors(s): Chacon Hernandez, Eyleen
Advisor(s): Aranibar Del Carpio, Edgar Omar
Keywords: Antibiótico; Infecciones; Asociaciones antibióticas; Sinergismo; Posología; Resistencia bacteriana; Antibiotic; Infections; Antibiotic associations; Synergism; Posology; Bacterial resistance
Issue Date: 6-Sep-2017
Institution: Universidad Inca Garcilaso de la Vega
Abstract: Los Antibióticos, son compuestos o sustancia producida por microorganismos y sintetizados también químicamente, que suprimen selectivamente el crecimiento o destruyen a otros microorganismos a bajas concentraciones. Las infecciones odontogénicas constituyen uno de los problemas con mayor frecuencia a las que el odontólogo general se enfrenta en su práctica diaria. El uso de antibióticos está dado por prescripción empírica que se basa en epidemiologia clínica y bacteriana. Luego de alojada una infección en la cavidad oral, se administrar diversos fármacos provocando la muerte o deteniendo la reproducción de estas células patógenas, salvaguardando así, toda la integridad del sistema estomatognático.
En la actualidad el uso de combinaciones o asociaciones antibióticas es común, gracias a la aparición de nuevos antibióticos, las particularidades del paciente y el aumento de resistencia bacteriana. Una asociación antibiótica es usar dos o más fármacos antimicrobianos para aumentar sus efectos individuales de manera positiva, sin tener consecuencias que perjudiquen la salud general del paciente. La finalidad de su uso es: Obtener el sinergismo antibacteriano (Adición o Potenciación), Reducir en lo posible la toxicidad de determinado fármaco, Prevenir la resistencia antibiótica, Garantizar la total cobertura de amplio espectro en donde se desconoce el agente causal. Según los antecedentes el uso de asociaciones antibióticas en Odontologia es muy escaso, pero teniendo en cuenta los estudios ya realizados se ha seleccionado tres asociaciones que cumplen cada uno de las finalidades además abarca los microorganismos presentes en infecciones orales mixtas y son de fácil acceso tanto al odontólogo como para el paciente. AMOXICILINA+ ACIDO CLAVULANICO, AMOXICILINA+ METRONIDAZOL, CLINDAMICINA + CIPROFLOXACINO. Cada una de estas asociaciones se elige teniendo en cuenta el estado del paciente, edad, tipo de microorganismo que causa la infección, la estructura que afecta, la difusión del fármaco en el sitio de acción. Basándonos en la posología se plantea protocolos de administración de cada asociación. Al realizar combinaciones antibióticas lo más
importante es evitar el Antagonismo entre los medicamentos, disminuir la resistencia bacteriana en los pacientes, aumentar el espectro de acción antibacterial. La combinación antibiótica más usada y la más recomendada a nivel odontoestomatologico es la Amoxicilina más ácido Clavulanico
Antibiotics are compounds or substances produced by microorganisms and also synthesized chemically, which selectively suppress growth or destroy other microorganisms at low concentrations. Odontogenic infections are one of the problems most frequently encountered by the general dentist in his daily practice. The use of antibiotics is given by empirical prescription based on clinical and bacterial epidemiology. After receiving an infection in the oral cavity, several drugs will be administered causing death or stopping the reproduction of these pathogenic cells, thus safeguarding the integrity of the stomatognathic system. At present the use of antibiotic combinations or associations is common, thanks to the appearance of new antibiotics, the particularities of the patient and the increase of bacterial resistance. An antibiotic association is to use two or more antimicrobial drugs to increase their individual effects in a positive way, without having consequences that harm the general health of the patient. The purpose of its use is: Obtain the antibacterial synergism (Addition or Potentiation), Reduce the toxicity of a particular drug as much as possible, Prevent antibiotic resistance, Ensure full spectrum coverage where the causal agent is unknown. According to the background, the use of antibiotic combinations in Odontology is very scarce, but taking into account the studies already done, three associations have been selected that fulfill each one of the purposes. It also covers the microorganisms present in mixed oral infections and they are easily accessible to both dentist as for the patient. AMOXICILLIN + CLAVULANIC ACID, AMOXICILLIN + METRONIDAZOL, CLINDAMYCIN + CYPROFLOXACIN. Each of these associations is chosen taking into account the patient's condition, age, type of microorganism causing the infection, structure affecting, diffusion of the drug at the site of action. Based on the posology, we propose management protocols for each association. When making antibiotic combinations the most important thing is to avoid the Antagonism between the medicines, to diminish the bacterial resistance in the patients, to increase the spectrum of antibacterial action. The most commonly used antibiotic combination and the most recommended at odontoestomatologic level is Amoxicillin plus Clavulanic acid.
Antibiotics are compounds or substances produced by microorganisms and also synthesized chemically, which selectively suppress growth or destroy other microorganisms at low concentrations. Odontogenic infections are one of the problems most frequently encountered by the general dentist in his daily practice. The use of antibiotics is given by empirical prescription based on clinical and bacterial epidemiology. After receiving an infection in the oral cavity, several drugs will be administered causing death or stopping the reproduction of these pathogenic cells, thus safeguarding the integrity of the stomatognathic system. At present the use of antibiotic combinations or associations is common, thanks to the appearance of new antibiotics, the particularities of the patient and the increase of bacterial resistance. An antibiotic association is to use two or more antimicrobial drugs to increase their individual effects in a positive way, without having consequences that harm the general health of the patient. The purpose of its use is: Obtain the antibacterial synergism (Addition or Potentiation), Reduce the toxicity of a particular drug as much as possible, Prevent antibiotic resistance, Ensure full spectrum coverage where the causal agent is unknown. According to the background, the use of antibiotic combinations in Odontology is very scarce, but taking into account the studies already done, three associations have been selected that fulfill each one of the purposes. It also covers the microorganisms present in mixed oral infections and they are easily accessible to both dentist as for the patient. AMOXICILLIN + CLAVULANIC ACID, AMOXICILLIN + METRONIDAZOL, CLINDAMYCIN + CYPROFLOXACIN. Each of these associations is chosen taking into account the patient's condition, age, type of microorganism causing the infection, structure affecting, diffusion of the drug at the site of action. Based on the posology, we propose management protocols for each association. When making antibiotic combinations the most important thing is to avoid the Antagonism between the medicines, to diminish the bacterial resistance in the patients, to increase the spectrum of antibacterial action. The most commonly used antibiotic combination and the most recommended at odontoestomatologic level is Amoxicillin plus Clavulanic acid.
Link to repository: https://hdl.handle.net/20.500.11818/1335
Discipline: Estomatología
Grade or title grantor: Universidad Inca Garcilaso de la Vega. Facultad de Estomatología
Grade or title: Licenciado en Cirujano Dentista
Register date: 26-Sep-2017
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