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Bravo, F., (2008). Niveles de inmunoglobulina G en saliva total como marcador biológico de la enfermedad periodontal [Tesis, Universidad Nacional Mayor de San Marcos]. https://hdl.handle.net/20.500.12672/2227
Bravo, F., Niveles de inmunoglobulina G en saliva total como marcador biológico de la enfermedad periodontal [Tesis]. PE: Universidad Nacional Mayor de San Marcos; 2008. https://hdl.handle.net/20.500.12672/2227
@misc{renati/493284,
title = "Niveles de inmunoglobulina G en saliva total como marcador biológico de la enfermedad periodontal",
author = "Bravo Castagnola, Francis Geraldo",
publisher = "Universidad Nacional Mayor de San Marcos",
year = "2008"
}
Title: Niveles de inmunoglobulina G en saliva total como marcador biológico de la enfermedad periodontal
Authors(s): Bravo Castagnola, Francis Geraldo
Advisor(s): García Linares, Sixto Ángel
Keywords: Enfermedad periodontal; Saliva; Inmunoglobulina G
OCDE field: https://purl.org/pe-repo/ocde/ford#3.02.14
Issue Date: 2008
Institution: Universidad Nacional Mayor de San Marcos
Abstract: El estudio evaluó la concentración de inmunoglobulina G (IgG) en saliva total en la enfermedad periodontal y su papel como marcador biológico en esta patología
Se incluyeron 50 individuos sanos y 40 pacientes periodontales como grupos control y estudio respectivamente. El grupo de estudio se dividió en subgrupos de 20 individuos: gingivitis y periodontitis.
El examen clínico evaluó placa dentaria, sangrado al sondaje y profundidad de sondaje. Las evaluaciones se efectuaron antes y después del tratamiento periodontal de Fase I. En ambos momentos se tomaron muestras de saliva total para determinar la concentración de IgG mediante el análisis espectrofotométrico de su absorbancia.
Se encontró que a mayor progresión de la enfermedad periodontal los niveles de IgG eran más elevados encontrándose una diferencia significativa entre pacientes sanos, con gingivitis y periodontitis. Sin embargo el grado de severidad de la gingivitis no constituía un factor relevante para la variación del nivel de IgG. Entre los casos leves y severos de periodontitis se encontró una diferencia significativa en los niveles de IgG.
-- This study evaluated the concentration of inmunogluline G (IgG) in whole saliva in peridontal disease and its role as a biological marker in this patology. To realize the study, 50 healthy patients and 40 patients were incluyed as control and study group respectively. The study group was divided in subgroup with 20 patients: gingivitis and periodontitis. The clinical examination was realized evaluating dental plaque, probing bleeding and probing depth. The evaluation were performed before and after the phase I periodontal treatment. At each moment, we took whole saliva samples to determine the IgG concentration through espectrophotometric analysis of its absorbance. We found that the greater progression of the periodontal disease, more elevated was the IgG level IgG establishing a significant difference between the healthy patients and individuals with gingivitis and periodontitis. However, the severity of gingivitis didn’t constitute a outstanding factor for significant differences in IgG concentration between slight and severe cases. On the other hand, between slight and severe cases of patients with periodontitis, we found a significant difference at IgG levels.
-- This study evaluated the concentration of inmunogluline G (IgG) in whole saliva in peridontal disease and its role as a biological marker in this patology. To realize the study, 50 healthy patients and 40 patients were incluyed as control and study group respectively. The study group was divided in subgroup with 20 patients: gingivitis and periodontitis. The clinical examination was realized evaluating dental plaque, probing bleeding and probing depth. The evaluation were performed before and after the phase I periodontal treatment. At each moment, we took whole saliva samples to determine the IgG concentration through espectrophotometric analysis of its absorbance. We found that the greater progression of the periodontal disease, more elevated was the IgG level IgG establishing a significant difference between the healthy patients and individuals with gingivitis and periodontitis. However, the severity of gingivitis didn’t constitute a outstanding factor for significant differences in IgG concentration between slight and severe cases. On the other hand, between slight and severe cases of patients with periodontitis, we found a significant difference at IgG levels.
Link to repository: https://hdl.handle.net/20.500.12672/2227
Discipline: Odontología
Grade or title grantor: Universidad Nacional Mayor de San Marcos. Facultad de Odontología. Escuela Académico Profesional de Odontología
Grade or title: Cirujano Dentista
Register date: 20-Aug-2013
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