Bibliographic citations
Polo, S., (2005). Distribución de las frecuencias alélicas de los genes HumTH01 y HumTPOX en una muestra de la provincia de Yungay (Ancash-Perú) empleando la técnica del duplex (TT) [Tesis, Universidad Nacional Mayor de San Marcos]. https://hdl.handle.net/20.500.12672/815
Polo, S., Distribución de las frecuencias alélicas de los genes HumTH01 y HumTPOX en una muestra de la provincia de Yungay (Ancash-Perú) empleando la técnica del duplex (TT) [Tesis]. PE: Universidad Nacional Mayor de San Marcos; 2005. https://hdl.handle.net/20.500.12672/815
@misc{renati/491410,
title = "Distribución de las frecuencias alélicas de los genes HumTH01 y HumTPOX en una muestra de la provincia de Yungay (Ancash-Perú) empleando la técnica del duplex (TT)",
author = "Polo Santillán, Susan Ibet",
publisher = "Universidad Nacional Mayor de San Marcos",
year = "2005"
}
---Short tandem repeats (STRs) are genetic markers distributed throught the whole genome. Over the last years, they have been used to study the genetic linkage of diseases, human identification and populations genetic due to its high degree of polymorphism. In this work, the results presented were obtained in the allele determination with the STRs: HumTH01(Human tyrosine hydroxylase gene) and HumTPOX (Human thyrid peroxidase gene) in the population sample constituted by 35 non-related individuals from Yungay (Ancash-Peru). The technique used were PCR, 7M urea 6% poliacrylamide gel electroforesis and visualized with silver nitrate staining. In Yungay's population, we found 3 alleles 6, 7 and 9.3 for HumTH01 with a value of heterozigocity of 0.5429 and homocigocity of 0.4571, and for marker HumTPOX 4 alleles 8, 9, 11 and 12with a value of heterozigocity of 0.3429 and homocigocity of 0.6571. The frequency distribution for marker HumTH01 for allele 6 equal to 0.3286, allele 7 equal to 0.5143 and allele 9.3 equal to 0.1571; and for marker TPOX for allele 8 equal to 0.7571, allele 9 equal to 0.0143, allele 11 equal to 0.2143 and allele 12 equal to 0.0143. The population is found in Hardy-Weinberg equilibrium, and there are no significant differences between the allelic frequencies of both markers between Yungay's population and the Hispano-American reported by Steven et al. (1998)
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