Bibliographic citations
Caballero, F., (2003). Evaluación experimental de la patogenicidad de un virus velogénico viscerotrópico de la enfermedad de Newcastle y su respuesta inmune humoral en aves columbiformes [Tesis, Universidad Nacional Mayor de San Marcos]. https://hdl.handle.net/20.500.12672/846
Caballero, F., Evaluación experimental de la patogenicidad de un virus velogénico viscerotrópico de la enfermedad de Newcastle y su respuesta inmune humoral en aves columbiformes [Tesis]. PE: Universidad Nacional Mayor de San Marcos; 2003. https://hdl.handle.net/20.500.12672/846
@misc{renati/487465,
title = "Evaluación experimental de la patogenicidad de un virus velogénico viscerotrópico de la enfermedad de Newcastle y su respuesta inmune humoral en aves columbiformes",
author = "Caballero Romero, Fabiola",
publisher = "Universidad Nacional Mayor de San Marcos",
year = "2003"
}
-- This study was designed to asses the susceptibility, pathologic effect and serologic response of wild pigeons (sp. Columba livia) to Newcastle virus. A total of twenty eight adult wild pigeons were captured, fourteen were inoculated with a velogenic viscerotropic strain of Newcastle virus by oral and nasal route. The remaining pigeons were used as control group. The birds were observed to record clinical signs and mortality, also blood samples were collected for hemaglutination inhibition technique and tissue samples from lungs, tracheas and cloacal swabs were harvested for the viral recovery and histological studies. The 64 % of the inoculated group showed clinical signs and a mortality of 42.8 %. The clinical signs (sneezes, ruffled plumage, isolation and lethargy) started the fourth day post inoculation. The 43 % showed nervous signs: opisthotonos, tremors of head and neck that was exaggerated to the stimulus of noises and the 21 % showed diarrhea. In the necropsy were observed a widespread congestion and splenomegaly. The microscopic injuries were edema, gliosis, mononuclear perivascular cuffing in brain and cerebellum, loss ciliar, lymphoid infiltration in trachea, lungs congestion, proventricular congestion, and lymphocitic infiltration in intestines and lymphoid depletion in spleen. The inoculated group showed an increase in the antibody titers the first week post inoculation reaching the highest titer mean (P.G.T=4.9) in the second week after this they descended. The viral recovery was made upon lungs and tracheas tissues and from a cloacal swab in dead birds. It was showed that the specie Columba livia was susceptible to the experimental inoculation with a velogenic strain of Newcastle diasease virus.
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