Bibliographic citations
Ramos, A., (2012). Actividad antibacteriana del extracto de Erythroxylum coca sobre Porphyromonas Gingivalis, estudio in vitro [Tesis, Universidad Nacional Mayor de San Marcos]. https://hdl.handle.net/20.500.12672/2824
Ramos, A., Actividad antibacteriana del extracto de Erythroxylum coca sobre Porphyromonas Gingivalis, estudio in vitro [Tesis]. PE: Universidad Nacional Mayor de San Marcos; 2012. https://hdl.handle.net/20.500.12672/2824
@misc{renati/484349,
title = "Actividad antibacteriana del extracto de Erythroxylum coca sobre Porphyromonas Gingivalis, estudio in vitro",
author = "Ramos Clemente, Armando Willy",
publisher = "Universidad Nacional Mayor de San Marcos",
year = "2012"
}
--- Periodontitis is a highly prevalent disease worldwide, in our country reaches 85% of the population. It is a multifactorial disease, being the primary etiologic factor, the microbial agent. One of the most important agents is Porphyromonas gingivalis, a strict anaerobic bacterial species, Gram negative. In turn, the use of systemic antibiotics is indicated only in certain types of periodontitis and the treatment is not always successful. Nowadays, both general medicine and dentistry, are investigating new antibacterial treatment alternatives, given the increase in bacterial resistance to conventional antibiotics and the adverse reactions that occur in some patients. The study investigated the antibacterial activity in vitro, of the extract of the coca leaves (Erythroxylum coca), on the Porphyromonas gingivalis strain ATCC, using the agar diffusion test and dilution test in liquid medium. The results of the first study indicated that the extract of Erythroxylum coca has zero sensitivity (-) for most of the tested concentrations, and sensitivity limit (sensitivity: +) for the maximum concentration of the extract (100%) on growth in vitro, of the bacterium Porphyromonas gingivalis. The results of the second study determined a minimum concentration of the extract able to inhibit the growth of said bacteria. This value was 6.25%, which represents the minimum inhibitory concentration (MIC).
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