Bibliographic citations
Espinoza, R., Flores, A. (2022). Asociación entre la anemia y los desenlaces clínicos adversos de la úlcera de pie diabético en pacientes adultos peruanos en un Hospital de Lima [Tesis, Universidad Peruana de Ciencias Aplicadas (UPC)]. http://hdl.handle.net/10757/659668
Espinoza, R., Flores, A. Asociación entre la anemia y los desenlaces clínicos adversos de la úlcera de pie diabético en pacientes adultos peruanos en un Hospital de Lima [Tesis]. PE: Universidad Peruana de Ciencias Aplicadas (UPC); 2022. http://hdl.handle.net/10757/659668
@misc{renati/399187,
title = "Asociación entre la anemia y los desenlaces clínicos adversos de la úlcera de pie diabético en pacientes adultos peruanos en un Hospital de Lima",
author = "Flores Gavino, Aldo Paul",
publisher = "Universidad Peruana de Ciencias Aplicadas (UPC)",
year = "2022"
}
Background Diabetic foot ulcer (DFU) is a clinical complication of diabetes mellitus (DM). Anemia has been associated with the progression of this disease. The objective of our study was to evaluate the association between anemia and adverse clinical outcomes of DFU in hospitalized patients. Methods We carried out a secondary database analysis from two retrospective cohort studies of DFU patients hospitalized in a national reference public hospital in Lima during 2015 and 2019. The exposure variable was anemia defined according to the hemoglobin value at admission. For our outcome variable, we grouped non-healing ulcers and amputation into the “adverse clinical outcome”. We estimated crude (RR) and adjusted relative risks (aRR) with 95% confidence intervals (CI95%) using generalized linear Poisson family models with accelerated and bias-corrected non-parametric bootstrap. Results We included 160 patients, which average age was 58 ± 12.7 years. Anemia was detected in 102 (63.8%) patients, 111 patients (69.4%) had an adverse clinical outcome, 49 patients (44.1%) were amputated, and 62 patients (55.9%) had non-healing ulcers. Anemia was significantly associated with the composite outcome (aRR = 1,37: CI95% = 1,05 - 1,80; p=0,019) and amputation (aRR = 1,78: CI95% = 1,12 - 3,28; p=0,017). We found no statistical evidence of a significant association between anemia and non-healing ulcers (aRR = 1,43: CI95% = 0,96 - 2,12; p=0,072). Conclusions Anemia increases the risk of amputation and adverse clinical outcome in hospitalized patients with DFU.
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