Bibliographic citations
Betancourt, A., (2023). Eficacia del tratamiento no quirúrgico con antibioticoterapia comparado con la apendicetomía en apendicitis aguda no complicada en pacientes pediátricos, revisión sistemática y metaanálisis [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/10185
Betancourt, A., Eficacia del tratamiento no quirúrgico con antibioticoterapia comparado con la apendicetomía en apendicitis aguda no complicada en pacientes pediátricos, revisión sistemática y metaanálisis [Tesis]. PE: Universidad Privada Antenor Orrego - UPAO; 2023. https://hdl.handle.net/20.500.12759/10185
@misc{renati/381975,
title = "Eficacia del tratamiento no quirúrgico con antibioticoterapia comparado con la apendicetomía en apendicitis aguda no complicada en pacientes pediátricos, revisión sistemática y metaanálisis",
author = "Betancourt Ucañan, Ayelen Stefania",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2023"
}
To determine if conservative treatment is more effective than appendectomy in relation to the success of both approaches compared, presence of complications during hospitalization, decreased length of hospital stay, and days of disability in uncomplicated acute appendicitis in children. MATERIAL AND METHODS: The present systematic review included randomized and non-randomized intervention clinical trials. A strategic search was carried out in the following databases: Pubmed, Web of Science, Embase, Scopus, Ovid, Cochrane Library, the articles were synthesized using the Rayyan Qcri software, Microsoft Excel 2016 was used for data extraction, the analysis For bias of randomized clinical trials, the Rob 2.0 tool of the Cochrane Collaboration and Robins-I was used for non-randomized clinical trials; For the meta-analysis, the statistical and quantitative analysis was performed using the Rev Man 5.4 Software. RESULTS: 5 articles were included in the meta-analysis, 3 randomized and 2 non-randomized clinical trials, the success rate was higher in the group with surgical management (100%) compared to 88.6% in conservative management (RR: 13.21, CI 95% 3.15-55.38, P=0.0004). Conservative treatment was associated with significantly fewer disability days among patients yielding a significant mean difference of -6.52, 95% CI 11.84-1.19, P=0.02. The length of hospital stay was longer in the conservative group (MD 0.52, 95% CI 0.32-0.72, P<0.00001). No significant difference was found regarding the presence of complications during hospitalization after the management carried out. CONCLUSIONS: Conservative treatment is safe and feasible as initial management, however, it presents a high risk of generating complications such as perforated appendicitis and is related to a longer hospital stay due to the administration of intravenous antibiotics for a minimum of 48 hours.
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