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Coronado, E., (2024). Utilidad del patrón de superficie de mucosa gástrica para detección de Helicobacter pylori [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/25931
Coronado, E., Utilidad del patrón de superficie de mucosa gástrica para detección de Helicobacter pylori [Tesis]. PE: Universidad Privada Antenor Orrego; 2024. https://hdl.handle.net/20.500.12759/25931
@mastersthesis{renati/380545,
title = "Utilidad del patrón de superficie de mucosa gástrica para detección de Helicobacter pylori",
author = "Coronado Rivera, Erika Fiorella",
publisher = "Universidad Privada Antenor Orrego",
year = "2024"
}
Title: Utilidad del patrón de superficie de mucosa gástrica para detección de Helicobacter pylori
Authors(s): Coronado Rivera, Erika Fiorella
Advisor(s): Vásquez Tirado, Gustavo Adolfo
Keywords: Helicobacter pylori; endoscopia gastrointestinal; biopsia
OCDE field: http://purl.org/pe-repo/ocde/ford#3.02.27
Issue Date: 2024
Institution: Universidad Privada Antenor Orrego
Abstract: Introducción: Helicobacter pylori es una bacteria que habita en el epitelio gástrico
y origina gastritis, úlcera péptica y cáncer gástrico. Se considera la infección crónica
más prevalente a nivel mundial. Puede persistir durante toda la vida y ser
responsable de múltiples enfermedades digestivas y extradigestivas.
Objetivo: El objetivo principal del estudio fue evaluar la utilidad del patrón de
superficie de mucosa gástrica para detección de Helicobacter pylori.
Métodos: Se realizó un estudio observacional, analítico, transversal, test
diagnóstico en 232 pacientes en un hospital público de III nivel en el Perú. Se utilizó
un endoscopio OLYMPUS GIF HQ-190 para evaluar el patrón de superficie de
mucosa gástrica. En cada paciente del estudio se obtuvo biopsias de antro y cuerpo
gástrico para estudio anatomo-patológico en busca de Helicobacter pylori.
Resultados: Se evaluaron 232 pacientes, 153 de ellos tuvieron H. pylori y 79 no
presentaron la infección. La mayoría de los infectados tenían género femenino. La
sensibilidad, especificidad, valor predictivo positivo y valor predictivo negativo
para detectar Helicobacter pylori utilizando el patrón de superficie de mucosa
gástrica fue de 92.81 %, 40.51%, 75.13 %, 74.42 % respectivamente. Los valores
razón de verosimilitud positiva y negativa fueron de 1.56 y 0.18.
Conclusiones: El patrón de superficie de mucosa gástrica no es útil para detectar
Helicobacter pylori
“Introduction: Helicobacter pylori is a bacterium that lives in the gastric epithelium and can cause gastritis, peptic ulcer and gastric cancer. It is considered the most prevalent chronic infection worldwide. It can persist throughout life and be responsible for multiple digestive and extradigestive diseases. Objective: The main objective of the study was to evaluate the utility of the gastric mucosal surface pattern for the detection of Helicobacter pylori. Methods: An observational, analytical, cross-sectional, diagnostic test study was carried out in 232 patients in a third level public hospital in Peru. An OLYMPUS GIF HQ-190 endoscope was used to assess the gastric mucosal surface pattern. In each patient in the study, biopsies of the gastric antrum and body were obtained for anatomopathological study in search of Helicobacter pylori. Results: 232 patients were evaluated, 153 of them had H. pylori and 79 did not present the infection. Most of the patients were female. The sensitivity, specificity, positive predictive value and negative predictive value to detect Helicobacter pylori using the gastric mucosa surface pattern was 92.81%, 40.51%, 75.13%, 74.42% respectively. The positive and negative likelihood ratio values were 1.56 and 0.18. Conclusions: The gastric mucosa surface pattern is not useful to detect Helicobacter pylori“
“Introduction: Helicobacter pylori is a bacterium that lives in the gastric epithelium and can cause gastritis, peptic ulcer and gastric cancer. It is considered the most prevalent chronic infection worldwide. It can persist throughout life and be responsible for multiple digestive and extradigestive diseases. Objective: The main objective of the study was to evaluate the utility of the gastric mucosal surface pattern for the detection of Helicobacter pylori. Methods: An observational, analytical, cross-sectional, diagnostic test study was carried out in 232 patients in a third level public hospital in Peru. An OLYMPUS GIF HQ-190 endoscope was used to assess the gastric mucosal surface pattern. In each patient in the study, biopsies of the gastric antrum and body were obtained for anatomopathological study in search of Helicobacter pylori. Results: 232 patients were evaluated, 153 of them had H. pylori and 79 did not present the infection. Most of the patients were female. The sensitivity, specificity, positive predictive value and negative predictive value to detect Helicobacter pylori using the gastric mucosa surface pattern was 92.81%, 40.51%, 75.13%, 74.42% respectively. The positive and negative likelihood ratio values were 1.56 and 0.18. Conclusions: The gastric mucosa surface pattern is not useful to detect Helicobacter pylori“
Link to repository: https://hdl.handle.net/20.500.12759/25931
Discipline: Maestría en Medicina
Grade or title grantor: Universidad Privada Antenor Orrego. Escuela de Postgrado
Grade or title: Maestra en Ciencias con Mención en Investigación Clínica
Juror: Caballero Alvarado, José Antonio; Bardales Zuta, Victor Hugo; Jara Morillo, Jorge Luis
Register date: 4-Apr-2024
This item is licensed under a Creative Commons License