Fosfatasa alcalina como factor de riesgo para complicaciones en colecistitis aguda

Abstract

Determinar si la fosfatasa alcalina es un factor de riesgo para complicaciones en pacientes con colecistitis aguda atendidos por emergencia del Hospital Regional Docente de Trujillo. Materiales y métodos: Se analizaron las historias clínicas de 324 pacientes con diagnóstico de colecistitis aguda atendidos en el Hospital Regional Docente de Trujillo entre 2015 y 2020. Se determinó aquellos quepresentan colecistitis aguda complicada y no complicada, y en cada uno deellos se estudiaron si los valores de fosfatasa alcalina se encontraban elevados o no. Los datos se procesaron en Excel y se analizaron en EPIDAT 4.2 y SPSS Statistics 26. Resultados: De todos los pacientes con colecistitis aguda que fueron estudiados, el 66.67% no presentó complicaciones y el 33.33% sí presentó colecistitis aguda con complicaciones. de todos los pacientes con colecistitis aguda complicada, el 92.6% presentan fosfatasa alcalina elevada y el 7.4% presentan niveles normales de fosfatasa alcalina. se determinó que la relación entre la fosfatasa alcalina elevada como factor de riesgo para colecistitis aguda complicada es estadísticamente significativo (p<0,001). Conclusión: La presencia de fosfatasa alcalina elevada es un factor de riesgo importante para padecer colecistitis aguda complicada.

To determine whether alkaline phosphatase is a risk factor for complications in patients with acute cholecystitis attended by the emergency department of the Hospital Regional Docente de Trujillo. Material and Methods: The medical records of 324 patients with a diagnosis of acute cholecystitis attended at the Hospital Regional Docente de Trujillo between 2015 and 2020 were analyzed. Those presenting complicated and uncomplicated acute cholecystitis were determined, and in each of them it was studied whether alkaline phosphatase values were elevated or not. The data were processed in Excel and analyzed inEPIDAT 4.2 and SPSS Statistics 26. Results: Of all patients with acute cholecystitis that were studied, 66.67% did not present complications and 33.33% did present acute cholecystitis with complications. of all patients with complicated acute cholecystitis, 92.6% presented elevated alkaline phosphatase and 7.4% presented normal alkaline phosphatase levels. the relationship between elevated alkaline phosphatase as a risk factor for complicated acute cholecystitis was found to be statistically significant (p<0.001). Conclusion: The presence of elevated alkaline phosphatase is an important risk factor for complicated acute cholecystitis.