Bibliographic citations
Leiva, M., (2020). Efecto ansiolítico in vivo del extracto etanólico de passiflora salpoense (passifloraceae) [Tesis, Universidad Privada Antenor Orrego - UPAO]. https://hdl.handle.net/20.500.12759/6028
Leiva, M., Efecto ansiolítico in vivo del extracto etanólico de passiflora salpoense (passifloraceae) [Tesis]. : Universidad Privada Antenor Orrego - UPAO; 2020. https://hdl.handle.net/20.500.12759/6028
@misc{renati/374683,
title = "Efecto ansiolítico in vivo del extracto etanólico de passiflora salpoense (passifloraceae)",
author = "Leiva Salinas, Milagros Joselyn",
publisher = "Universidad Privada Antenor Orrego - UPAO",
year = "2020"
}
Evaluate in vivo the anxiolytic effect of the ethanolic extract of Passiflora salpoense (Passifloraceae). Material and methods: A prospective, transversal, preclinical in vivo. It was used 20 Balb/c mice that were randomly distributed in 4 groups for administering them orally in the following way: G1: white group 0.2 ml saline solution, G2: group diazepam 1 mg/kg, G3: group 50 mg/kg of ethanolic extract of P. salpoense, and G4: group 100 mg/kg of ethanolic extract of P. salpoense. Then, the mice were induced to anxiety using the Marble burying test. Results: G3 and G4 groups significantly decreased the number of buried spheres with a mean of 9.60 ± 1.82 and 4.20 ± 1.30, respectively compared to the white control group (G1) whose mean was 17.20 ± 3.03. Likewise, the G3 and G4 groups presented a response similar to the G2 group whose mean was 3 ± 0.71. Conclusions: The doses 50 mg/kg and 100 mg/kg of the ethanolic extract of Passiflora salpoense significantly reduce anxiety levels (p < 0..05)
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