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Merino, B., (2024). Misoprostol más oxitocina en la profilaxis de hemorragia postparto abdominal [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/33191
Merino, B., Misoprostol más oxitocina en la profilaxis de hemorragia postparto abdominal [Tesis]. PE: Universidad Privada Antenor Orrego; 2024. https://hdl.handle.net/20.500.12759/33191
@misc{renati/374193,
title = "Misoprostol más oxitocina en la profilaxis de hemorragia postparto abdominal",
author = "Merino Bacilio, Bryan Joel",
publisher = "Universidad Privada Antenor Orrego",
year = "2024"
}
Title: Misoprostol más oxitocina en la profilaxis de hemorragia postparto abdominal
Authors(s): Merino Bacilio, Bryan Joel
Advisor(s): Rodríguez Barboza, Héctor Uladismiro
Keywords: Hemorragia post- cesárea; oxitocina; misoprostol
OCDE field: https://purl.org/pe-repo/ocde/ford#3.02.27
Issue Date: 2024
Institution: Universidad Privada Antenor Orrego
Abstract: La hemorragia post parto es una de las primeras causas de muerte materna en el
Perú y en el mundo, que afecta a las poblaciones menos desarrolladas. El
alumbramiento dirigido disminuye la perdida sanguínea durante el parto. No
obstante, a pesar de esta buena práctica, continúan ocurriendo muertes por
hemorragia post parto.
Objetivo: En el presente estudio plantea sistematizar la experiencia de conducción
del parto y alumbramiento con oxitocina y misoprostol que utilizan algunos
ginecólogos del HBT como practica de rutina durante la cesárea para disminuir la
hemorragia post parto abdominal.
Método: Se realizó un estudio explicativo de cohortes retrospectivas en 180
gestantes sometidas a cesárea entre mayo 2019 a diciembre 2023. (90 gestantes
que recibieron oxitocina y 90 gestantes en las que se utilizó oxitocina más
misoprostol transcesarea). Se midió la hemoglobina pre y post cesárea y secomparó
el nivel de complicaciones, medidas complementarias y la necesidad de la
transfusión de hemoderivados en ambos grupos. El análisis de las diferencias se
realizó con la prueba T para variables continuas y chi cuadrado para proporciones
en variables cualitativas, con un nivel de significancia estadística de 95%.
Resultados: Se encontraron 11 casos de hemorragia en el grupo con oxitocina y
5 en el grupo con misoprostol, 4 pacientes en el grupo con oxitocina recibieron
transfusión de eritrocitos, ninguno en el grupo con misoprostol P<0.05. La
frecuencia cardiaca post operatoria es 75.6 y de 96.9 en el grupo con misoprostol
P<0.001, con una PAM de 80.6. La estancia hospitalaria fue de 2.9 días en el grupo
con oxitocina y 2.2 en el grupo con misoprostol; el 4.4% del grupo con oxitocina
ingresaron a la UCEM y ninguno en el grupo con misoprostol P<0.05.
Conclusiones:
La conducción del alumbramiento con 3 Unidades de oxitocina, seguida de 400 ug
de misoprostol molido sublingual, disminuye la pérdida sanguínea durante el parto
abdominal
Postpartum hemorrhage is one of the leading causes of maternal death in Peru and in the world, affecting less developed populations. Directed delivery reduces blood loss during childbirth. However, despite this good practice, deaths from postpartum hemorrhage continue to occur. Objective: The present study aims to systematize the experience of conducting labor and delivery with oxytocin and misoprostol that some HBT gynecologists use as a routine practice during cesarean section to reduce abdominal postpartum hemorrhage. Method: An explanatory retrospective cohort study was carried out on 180 pregnant women, some of whom underwent cesarean section, between May 2019 and December 2023, (90 pregnant women who received oxytocin and 90 pregnant women in whom misoprostol was used). Hemoglobin was measured before and after cesarean section and the level of complications, complementary measures and the need for transfusion of blood products were compared in both groups. The analysis of differences was performed with the T test for continuous variables and chi square for proportions in qualitative variables, with a statistical significance level of 95%. Results: There were 11 cases of hemorrhage in the group with oxytocin and 5 in the group with misoprostol, 4 patients in the group with oxytocin received erythrocyte transfusion, none in the group with misoprostol P<0.05. The postoperative heart rate is 75.6 and 96.9 in the misoprostol group P<0.001, with a MAP of 80.6. Hospital stay was 2.9 days in the oxytocin group and 2.2 in the misoprostol group; 4.4% of the oxytocin group were admitted to the EMCU and none in the misoprostol group P<0.05. Conclusions: Conduction of labor with 3 Units of oxytocin, followed by 400 ug of sublingual ground misoprostol, decreases blood loss during abdominal delivery
Postpartum hemorrhage is one of the leading causes of maternal death in Peru and in the world, affecting less developed populations. Directed delivery reduces blood loss during childbirth. However, despite this good practice, deaths from postpartum hemorrhage continue to occur. Objective: The present study aims to systematize the experience of conducting labor and delivery with oxytocin and misoprostol that some HBT gynecologists use as a routine practice during cesarean section to reduce abdominal postpartum hemorrhage. Method: An explanatory retrospective cohort study was carried out on 180 pregnant women, some of whom underwent cesarean section, between May 2019 and December 2023, (90 pregnant women who received oxytocin and 90 pregnant women in whom misoprostol was used). Hemoglobin was measured before and after cesarean section and the level of complications, complementary measures and the need for transfusion of blood products were compared in both groups. The analysis of differences was performed with the T test for continuous variables and chi square for proportions in qualitative variables, with a statistical significance level of 95%. Results: There were 11 cases of hemorrhage in the group with oxytocin and 5 in the group with misoprostol, 4 patients in the group with oxytocin received erythrocyte transfusion, none in the group with misoprostol P<0.05. The postoperative heart rate is 75.6 and 96.9 in the misoprostol group P<0.001, with a MAP of 80.6. Hospital stay was 2.9 days in the oxytocin group and 2.2 in the misoprostol group; 4.4% of the oxytocin group were admitted to the EMCU and none in the misoprostol group P<0.05. Conclusions: Conduction of labor with 3 Units of oxytocin, followed by 400 ug of sublingual ground misoprostol, decreases blood loss during abdominal delivery
Link to repository: https://hdl.handle.net/20.500.12759/33191
Discipline: Medicina Humana
Grade or title grantor: Universidad Privada Antenor Orrego. Facultad de Medicina Humana
Grade or title: Médico Cirujano
Juror: Vásquez Alvarado, Javier Ernesto; Castañeda Cuba, Luis Enrique; Salazar Cruzado, Orlando Rodolfo
Register date: 4-Jul-2024
This item is licensed under a Creative Commons License