Bibliographic citations
Yamamoto, J., Prado, J. (2019). Asociación entre transaminasemia y resistencia a la insulina en una población urbana de Lima, Perú entre los años 2014 y 2016 [Tesis, Universidad Peruana de Ciencias Aplicadas (UPC)]. http://hdl.handle.net/10757/628126
Yamamoto, J., Prado, J. Asociación entre transaminasemia y resistencia a la insulina en una población urbana de Lima, Perú entre los años 2014 y 2016 [Tesis]. PE: Universidad Peruana de Ciencias Aplicadas (UPC); 2019. http://hdl.handle.net/10757/628126
@misc{renati/369586,
title = "Asociación entre transaminasemia y resistencia a la insulina en una población urbana de Lima, Perú entre los años 2014 y 2016",
author = "Prado Núñez, Jesús Sebastián",
publisher = "Universidad Peruana de Ciencias Aplicadas (UPC)",
year = "2019"
}
Aim: To evaluate the association between elevated serum transaminase levels and insulin resistance in a population of individuals without alterations in their laboratorial values of glycemia, insulinemia and thyroid panel. Methods: We performed a crude and adjusted generalized linear model of the Poisson family with robust variance, in order to evaluate the association between elevated serum transaminase levels and insulin resistance. The associations were presented as prevalence ratio (PR) with their respective 95% confidence intervals (95% CI). Results: We included 261 participants in the study. The median age was 39 years (31-45) and 23,7% of the participants were men. The prevalence of elevated serum transaminase for TGO and TGP were, 13.8% and 26.1%, respectively. The prevalence of insulin resistance was 34,1%. In the crude analysis we found statistical significance between elevated TGP and TGO and insulin resistance (PR=3,18; 95% CI: 2,33-4,34 and PR=2.44; 95% CI: 1.88-3.30; respectively). However, in the multivariate analysis adjusted for age, sex, body mass index and thyroid hormones, the association between the elevated serum transaminase level and insulin resistance remained statistically significance with TGP, but lost its significance with TGO; a PR = 1.90; CI95%: 1.31-2.77 and a PR = 1.23; CI95%: 0.93-1.61; respectively. Conclusion: Elevated serum levels of TGP were associated with insulin resistance. TGP could be used in clinical practice as an additional tool to assess insulin resistance in people without laboratorial alterations in glycemia, insulinemia and thyroid panel.
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