Citas bibligráficas
Salcedo, N., (2025). Reanimación con líquidos intensiva o moderada en la pancreatitis aguda: revisión sistemática y meta-análisis [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/59033
Salcedo, N., Reanimación con líquidos intensiva o moderada en la pancreatitis aguda: revisión sistemática y meta-análisis [Tesis]. PE: Universidad Privada Antenor Orrego; 2025. https://hdl.handle.net/20.500.12759/59033
@misc{renati/1757908,
title = "Reanimación con líquidos intensiva o moderada en la pancreatitis aguda: revisión sistemática y meta-análisis",
author = "Salcedo Campos, Naomi Milagros",
publisher = "Universidad Privada Antenor Orrego",
year = "2025"
}
Objective: Adequate fluid resuscitation is essential in the management of acute pancreatitis. The objective of this study is to evaluate whether intensive fluid resuscitation is more effective compared to moderate resuscitation in patients with acute pancreatitis. Methods: A systematic review and meta-analysis were conducted. A search was performed in medical databases such as PubMed, Scopus, Web of Science, and EMBASE from February 2023 to August 2024. The Rayyan software was used to analyze articles that met the inclusion and exclusion criteria. Ultimately, 7 articles that exclusively met the search and analysis parameters were included. Results: In the primary outcome, mortality was not significantly reduced with intensive fluid resuscitation compared to moderate therapy (RR: 2.60; 95% CI: 1.48– 4.57; I² = 0%); intensive fluid therapy did not reduce the length of hospital stay in patients with acute pancreatitis either (RR: 1.21; 95% CI: 0.72-1.69; I² = 65%). Additionally, it did not show a significant reduction in the risk of persistent systemic inflammatory response syndrome (SIRS) compared to moderate resuscitation (RR: 0.81; 95% CI: 0.26-2.53; I² = 26%). Regarding complications due to fluid overload, intensive therapy did not reduce the risk of their occurrence (RR: 2.81; 95% CI: 1.11- 7.09; I² = 0%). Finally, no statistical difference was found when comparing intensive and moderate resuscitation regarding clinical improvement in patients with acute pancreatitis (RR: 1.20; 95% CI: 0.63-2.29; I² = 72%). Conclusion: Intensive fluid resuscitation, compared to moderate resuscitation, was not more effective in reducing mortality, length of hospital stay, persistence of SIRS, complications from fluid overload, or showing clinical improvement
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