Bibliographic citations
Castillo, R., (2024). Biocompatibilidad de la interacción de nanopartículas de Titanato de Bario recubiertos con quitosano en cultivos celulares [Tesis, Universidad Privada Antenor Orrego]. https://hdl.handle.net/20.500.12759/34031
Castillo, R., Biocompatibilidad de la interacción de nanopartículas de Titanato de Bario recubiertos con quitosano en cultivos celulares [Tesis]. PE: Universidad Privada Antenor Orrego; 2024. https://hdl.handle.net/20.500.12759/34031
@phdthesis{renati/1342599,
title = "Biocompatibilidad de la interacción de nanopartículas de Titanato de Bario recubiertos con quitosano en cultivos celulares",
author = "Castillo Díaz, Ruth Elizabeth",
publisher = "Universidad Privada Antenor Orrego",
year = "2024"
}
This research evaluates the biocompatibility of barium titanate nanoparticles coated with chitosan in cellular cultures, focusing on HeLa cell lines and human lymphocytes. The general objective was to determine the impact of these nanoparticles on cell viability and chromosomal integrity. Tests were conducted to establish the optimal concentration that does not generate cytotoxicity, determine the median lethal dose, and analyze cell viability using the MTT assay and observation of chromosomal aberrations. The results indicated that BaTiO3@quit nanoparticles showed favorable biocompatibility up to a concentration of 100 μg/ml in HeLa cells, without significantly affecting cell viability or chromosomal structure in lymphocytes. This study concludes that BaTiO3 nanoparticles coated with chitosan do not present significant cytotoxic or genotoxic effects in the evaluated cellular models, suggesting their potential application in biomedical and bioelectronic fields
This item is licensed under a Creative Commons License