Bibliographic citations
Chuquimango, T., Toribio, K. (2024). Cambios citológicos en la mucosa oral de pacientes adultos mayores con diabetes tipo 2 y un grupo control que acuden al Hospital Nacional Cayetano Heredia, Lima - Perú, 2023 [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/16342
Chuquimango, T., Toribio, K. Cambios citológicos en la mucosa oral de pacientes adultos mayores con diabetes tipo 2 y un grupo control que acuden al Hospital Nacional Cayetano Heredia, Lima - Perú, 2023 []. PE: Universidad Peruana Cayetano Heredia; 2024. https://hdl.handle.net/20.500.12866/16342
@misc{renati/1281871,
title = "Cambios citológicos en la mucosa oral de pacientes adultos mayores con diabetes tipo 2 y un grupo control que acuden al Hospital Nacional Cayetano Heredia, Lima - Perú, 2023",
author = "Toribio Toribio, Katherine Luzbet",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2024"
}
Type 2 diabetes is a chronic non-communicable disease that consists of the body's inability to effectively use insulin. The population of elderly adults has increased in recent years. Objective: To analyze the cytological changes, microbial flora, and inflammatory cells of the oral mucosa of elderly patients with type 2 diabetes and a control group attending the Cayetano Heredia National Hospital. Materials and methods: Analytical study of a cross-sectional and observational type. A total of 424 oral smears were collected from 212 patients (106 elderly patients with type 2 diabetes and 106 elderly patients without diabetes from the control group), and samples of the lingual dorsum and yugal mucosa were obtained per each patient. Pap smear was used, and observed through an optical microscope. The variables were: anisocytosis, bi or multinucleation, anisokarosis, hyperchromatism, karyorexis, vacuolization of the cytoplasm, micronucleus, lobed nucleus, pycnotic nucleus, karyolytic cells, microbial flora and inflammatory cells. A bivariate analysis was performed where the chi-square statistical test was used. Results: A statistically significant difference was found between both groups in anisocytosis, bi- or multinucleation, anisokarosis, hyperchromaticism, karyorexis, cytoplasmic vacuolization, micronucleus, lobed nucleus, pycnotic nucleus and karyolytic cells. No statistically significant difference was found in microbial flora and inflammatory cells. Conclusion: The cytology of elderly patients with type 2 diabetes shows cellular alterations unlike non-diabetic patients.
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