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Cardoza, R., Velasquez, N. (2024). Eficacia del aceite esencial de orégano como agente antimicrobiano en estudios recientes [Universidad María Auxiliadora]. https://hdl.handle.net/20.500.12970/2407
Cardoza, R., Velasquez, N. Eficacia del aceite esencial de orégano como agente antimicrobiano en estudios recientes []. PE: Universidad María Auxiliadora; 2024. https://hdl.handle.net/20.500.12970/2407
@misc{renati/1112825,
title = "Eficacia del aceite esencial de orégano como agente antimicrobiano en estudios recientes",
author = "Velasquez Rodríguez, Natali Danixa",
publisher = "Universidad María Auxiliadora",
year = "2024"
}
Title: Eficacia del aceite esencial de orégano como agente antimicrobiano en estudios recientes
Other Titles: Efficacy of oregano essential oil as an antimicrobial agent in recent studies
Authors(s): Cardoza Huiman, Rosa; Velasquez Rodríguez, Natali Danixa
Advisor(s): Samaniego Joaquín, Jhonnel Williams
Keywords: Aceites esenciales; Origanum vulgare; Antimicrobiano; Carvacrol; Timol; Essential oils; Origanum vulgare; Antimicrobial; Thymol
OCDE field: https://purl.org/pe-repo/ocde/ford#3.01.05
Issue Date: 12-Dec-2024
Institution: Universidad María Auxiliadora
Abstract: Objetivo: evaluar la eficacia antimicrobiana del aceite esencial de orégano (Origanum vulgare), analizando su composición química, mecanismos de acción y efectividad frente a diversos patógenos.
Metodología: se realizó una revisión sistemática de 10 estudios científicos publicados en los últimos cinco años, seleccionados de bases de datos como PubMed, ScienceDirect y Scopus. Los estudios incluyeron microorganismos como bacterias Gram- positivas, Gram-negativas y hongos patógenos.
Resultados: el aceite esencial de orégano mostró alta eficacia antimicrobiana, especialmente frente a cepas multirresistentes como Staphylococcus aureus, Escherichia coli y hongos como Candida albicans y Aspergillus niger. Sus principales componentes bioactivos, carvacrol y timol, desestabilizan las membranas celulares, causando daños críticos que llevan a la muerte microbiana. Además, se identificó actividad sinérgica al combinar el aceite con otros antimicrobianos, aumentando su potencial terapéutico.
Conclusión: el aceite esencial de orégano es una alternativa natural prometedora para combatir la resistencia antimicrobiana, con aplicaciones en medicina e industria alimentaria. Sin embargo, se requieren estudios in vivo para
validar su efectividad en contextos clínicos y comerciales.
Objective: to comprehensively evaluate the antimicrobial efficacy of oregano essential oil (Origanum vulgare), analyzing its chemical composition, mechanisms of action of its bioactive components, and effectiveness against various pathogens. Methodology: a systematic review of 10 scientific studies published in the last five years was conducted, selected from academic databases such as PubMed, ScienceDirect, and Scopus. The studies included microorganisms such as Gram-positive and Gram-negative bacteria and pathogenic fungi. Results: oregano essential oil demonstrated high antimicrobial efficacy, particularly against multidrug-resistant strains such as Staphylococcus aureus, Escherichia coli, and fungi like Candida albicans and Aspergillus niger. Its main bioactive components, carvacrol and thymol, disrupt microbial cell membranes, causing critical damage that leads to cell death. Additionally, synergistic activity was reported when the oil was combined with other antimicrobial compounds, enhancing its therapeutic potential. Conclusión: oregano essential oil is a promising natural alternative to address the growing issue of antimicrobial resistance, with potential applications in medicine and the food industry. However, in vivo studies are recommended to validate its effectiveness in clinical and commercial settings.
Objective: to comprehensively evaluate the antimicrobial efficacy of oregano essential oil (Origanum vulgare), analyzing its chemical composition, mechanisms of action of its bioactive components, and effectiveness against various pathogens. Methodology: a systematic review of 10 scientific studies published in the last five years was conducted, selected from academic databases such as PubMed, ScienceDirect, and Scopus. The studies included microorganisms such as Gram-positive and Gram-negative bacteria and pathogenic fungi. Results: oregano essential oil demonstrated high antimicrobial efficacy, particularly against multidrug-resistant strains such as Staphylococcus aureus, Escherichia coli, and fungi like Candida albicans and Aspergillus niger. Its main bioactive components, carvacrol and thymol, disrupt microbial cell membranes, causing critical damage that leads to cell death. Additionally, synergistic activity was reported when the oil was combined with other antimicrobial compounds, enhancing its therapeutic potential. Conclusión: oregano essential oil is a promising natural alternative to address the growing issue of antimicrobial resistance, with potential applications in medicine and the food industry. However, in vivo studies are recommended to validate its effectiveness in clinical and commercial settings.
Link to repository: https://hdl.handle.net/20.500.12970/2407
Discipline: Farmacia y Bioquímica
Grade or title grantor: Universidad María Auxiliadora. Facultad de Farmacia y Bioquímica.
Grade or title: Químico Farmacéutico
Register date: 21-Jan-2025
This item is licensed under a Creative Commons License