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Córdova Serrano, Gerson (es_PE)
Davila Raime, Anita Flor (es_PE)
Villanueva Cotrina, Brian Benhamin (es_PE)
2024-07-01T21:10:50Z
2024-07-01T21:10:50Z
2024-06-17
https://hdl.handle.net/20.500.12970/2189
Objetivo: determinar el efecto antibacteriano del extracto hidroalcohólico de Polygala sp (canchalagua) y Croton elegans (mosquera) in vitro en Staphylococcus aureus (ATCC:25923) comparado con la ampicilina. Materiales y métodos: la investigación es de tipo explicativa, de enfoque cuantitativo, diseño experimental multifactorial. Se extrajo mediante la técnica de maceración hidroalcohólica. La actividad antibacteriana se determinó mediante el método de Kirby-Bouer. Resultados: se halló en el análisis fitoquímico del extracto hidroalcohólico de Polygala sp (canchalagua) y Croton elegans (mosquera) la presencia de saponinas, triterpenos, esteroides, y compuesto fenólicos Así mismo se obtuvo un 55% y 35% de humedad, ambas plantas solubles en alcohol. También se obtuvo un rendimiento de 12.63% y 13.16%. Además, se registró la inhibición bacteriana en sinergismo farmacológico con un halo de inhibición de 11.126 mm. Conclusiones: el extracto hidroalcohólico de Polygala sp (canchalagua) y Croton elegans (mosquera) presenta efecto antibacteriano frente a Staphylococcus aureus individualmente y en sinergismo farmacológico. (es_PE)
Objective: to determine the antibacterial effect of hydroalcoholic extract of Polygala sp (canchalagua) and Croton elegans (mosquera) in vitro on Staphylococcus aureus (ATCC:25923) compared to ampicillin. Materials and methods: the research is of explanatory type, quantitative approach, multifactorial experimental design. It was extracted by hydroalcoholic maceration technique. The antibacterial activity was determined by the Kirby-Bouer method. Results: phytochemical analysis of the hydroalcoholic extract of Polygala sp (canchalagua) and Croton elegans (mosquera) showed the presence of saponins, triterpenes, steroids, and phenolic compounds, as well as 55% and 35% of moisture, both plants soluble in alcohol. Yields of 12.63% and 13.16% were also obtained. In addition, bacterial inhibition was recorded in pharmacological synergism with an inhibition halo of 11.126 mm. Conclusions: the hydroalcoholic extract of Polygala sp (canchalagua) and Croton elegans (mosquera) shows antibacterial effect against Staphylococcus aureus individually and in pharmacological synergism. (es_PE)
application/pdf (es_PE)
spa (es_PE)
Universidad María Auxiliadora (es_PE)
info:eu-repo/semantics/openAccess (es_PE)
https://creativecommons.org/licenses/by/4.0/ (es_PE)
Staphylococcus aureus (es_PE)
Sinergismo farmacológico (es_PE)
Antibacteriano (es_PE)
Drug synergism (es_PE)
Efecto antibacteriano del extracto hidroalcohólico de Polygala sp (Canchalagua) y Croton elegans (Mosquera) in vitro en Staphylococcus aureus (ATCC:25923) comparado con la ampicilina (es_PE)
Antibacterial effect of the hydroalcoholic extract of Polygala sp (Canchalagua) and Croton elegans (Mosquera) in vitro on Staphylococcus aureus (ATCC:25923) compared to ampicillin (es_PE)
info:eu-repo/semantics/bachelorThesis (es_PE)
Universidad María Auxiliadora. Facultad de Ciencias de la Salud. (es_PE)
Farmacia y Bioquímica (es_PE)
Químico Farmacéutico (es_PE)
PE (es_PE)
https://purl.org/pe-repo/ocde/ford#3.01.05 (es_PE)
https://purl.org/pe-repo/renati/level#tituloProfesional (es_PE)
45276376
https://orcid.org/0000-0002-5591-0322 (es_PE)
44784501
70939013
917046 (es_PE)
Dionicio Escalante, Elisa Roxana (es_PE)
Alguiar Bernaola, Luz Rocío (es_PE)
Siancas Tao, Norio Salvador (es_PE)
https://purl.org/pe-repo/renati/type#tesis (es_PE)
Privada societaria
info:eu-repo/semantics/acceptedVersion (es_PE)



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