Bibliographic citations
Jara, C., (2023). Estudio de componentes terpenoidales actividad antibacteriana de la resina de Vismia macrophylla “Pichirina” sobre los agentes patógenos, Iquitos – Perú [Universidad Nacional de Trujillo]. https://hdl.handle.net/20.500.14414/19290
Jara, C., Estudio de componentes terpenoidales actividad antibacteriana de la resina de Vismia macrophylla “Pichirina” sobre los agentes patógenos, Iquitos – Perú []. PE: Universidad Nacional de Trujillo; 2023. https://hdl.handle.net/20.500.14414/19290
@phdthesis{renati/1051020,
title = "Estudio de componentes terpenoidales actividad antibacteriana de la resina de Vismia macrophylla “Pichirina” sobre los agentes patógenos, Iquitos – Perú",
author = "Jara Herrera, Cleto",
publisher = "Universidad Nacional de Trujillo",
year = "2023"
}
Vísmia macrophylla Kunth, a species that grows in the Amazon that contains a reddish-yellow resin, is used by Amazonian peoples to treat conditions caused by fungi. The objective of the study was to extract, characterize and evaluate the antibacterial activity of the terpenoid components on Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus and Staphylococcus epidermidis) bacteria. The sample was collected in the village of Nina Rumi, Nanay River, in the Peruvian Amazon. The terpenoid compounds were extracted by supercritical fluid with CO2, characterized using a gas chromatograph coupled to a mass spectrometer, and the antibacterial activity with Kirby-Bauer disk diffusion test and diffusion in holes. Thirteen terpenoid compounds were extracted, with the highest abundance being terpen-4-ol (36.08 %), α-terpineol (21.46 %), α-eudesmol (16.89 %), and -copaene (8.89 %). The antibacterial activity tests of the extruded terpenoid components were negative against the three types of bacteria, however, the resin showed moderate antibacterial activity against Staphylococcus aureus with inhibition haloes of 17.5 and 20 mm and good activity against Staphylococcus epidermidis with inhibition haloes of 22.5 mm and 28 mm. This finding allows considering that V. macrophylla resin should be considered as a natural source of active principles for the treatment of skin mycosis
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