Bibliographic citations
Galliani, G., (2021). Efecto de los rizomas de Schoenoplectus californicus sobre el sistema nervioso central de Mus musculus Balb/c en tres modelos psicofarmacológicos [Universidad Nacional de Trujillo]. https://hdl.handle.net/20.500.14414/19230
Galliani, G., Efecto de los rizomas de Schoenoplectus californicus sobre el sistema nervioso central de Mus musculus Balb/c en tres modelos psicofarmacológicos []. PE: Universidad Nacional de Trujillo; 2021. https://hdl.handle.net/20.500.14414/19230
@misc{renati/1048125,
title = "Efecto de los rizomas de Schoenoplectus californicus sobre el sistema nervioso central de Mus musculus Balb/c en tres modelos psicofarmacológicos",
author = "Galliani Huamanchumo, Gladys Isabel",
publisher = "Universidad Nacional de Trujillo",
year = "2021"
}
ABSTRACT The main objective of the present investigation was to determine the effect of the rhizomes of Schoenoplectus californicus (Totora) on the central nervous system in Mus musculus Balb / c, for which it was made of three murine models Open Field, Elevated Plus Maze Tale and Rota rod. The plant species was collected from the cattails located in the district of Huanchaco-Trujillo, then a hydroethanolic extract with 50 ° alcohol was elaborated and it was filtered, rotaevaporated and lyophilized. 28 specimens distributed in 4 experimental groups were used. The target group received physiological saline solution (SSF) at a dose of 5 mL / kg intraperitoneally (VIP), the problem group I received the lyophilisate of the hydroethanolic extract of cattail by intraperitoneally at a lower dose (50 mg / kg) and the problem group II received at a dose of 200 mg / kg, finally, the standard group received diazepam (DZP) at a dose of 1mg / kg VIP; 40 minutes after administration intraperitoneally, the evaluation of the advanced square variables, bipedal positions, intrusion holes, defecation and grooming was performed in the Open Field test, after 60 minutes of intraperitoneally administration the Elevated Cross Maze test was performed in which the variables time of permanence in open and closed arms, central square and number of entries in open and closed arms were evaluated, finally the Rota rod test was carried out in which the time of permanence in the rotating bar was evaluated; These variables allowed evaluating motor activity, stereotyped behavior and anxiety, showing that the group that received cattail at a dose of 50 mg / kg exhibited results similar to those recorded by the group that received DZP, a central nervous system depressant drug.
This item is licensed under a Creative Commons License