Bibliographic citations
Arribasplata, E., (2021). Reformulación y estudio de estabilidad acelerada de Acetilcisteína 100 mg/5 mL x 120 mL Jarabe, en un Laboratorio Farmacéutico Nacional. Lima, 2019 [Universidad Nacional de Trujillo]. https://hdl.handle.net/20.500.14414/19482
Arribasplata, E., Reformulación y estudio de estabilidad acelerada de Acetilcisteína 100 mg/5 mL x 120 mL Jarabe, en un Laboratorio Farmacéutico Nacional. Lima, 2019 []. PE: Universidad Nacional de Trujillo; 2021. https://hdl.handle.net/20.500.14414/19482
@misc{renati/1045946,
title = "Reformulación y estudio de estabilidad acelerada de Acetilcisteína 100 mg/5 mL x 120 mL Jarabe, en un Laboratorio Farmacéutico Nacional. Lima, 2019",
author = "Arribasplata Chamorro, Erika Jakeline",
publisher = "Universidad Nacional de Trujillo",
year = "2021"
}
ABSTRACT The purpose of this pre-professional practice report was to determine the accelerated stability of three batches of Acetylcysteine 100 mg / 5 mL x 120 mL Syrup, entered by reformulation to the stability cabinets with the environmental conditions that correspond to climatic zone IV a, where Our country is located (Peru; temperature of 40 ° C ± 2 ° C and a Relative Humidity of 75% ± 5% for this type of study). The study was carried out in a national pharmaceutical laboratory, carrying out the tests specified in the analytical technique, typical of the laboratory at 0, 3 and 6 months of the study, in order to obtain the Sanitary Registry for its commercialization. Concluding that at the end of the time (6 months) the three reformulated batches, being the minimum quantity of batches to carry out a study of stability to a drug, complied with the tests of organoleptic description, delivery volume, pH and dosage (% of Acetylcysteine between 90 % - 110%).
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