Bibliographic citations
Blanco, C., (2023). Estudio etnobotánico, fitoquímico y farmacológico de especies vegetales utilizadas popularmente en la prevención y tratamiento sintomático de Covid-19 [Universidad Nacional de Trujillo]. https://hdl.handle.net/20.500.14414/20742
Blanco, C., Estudio etnobotánico, fitoquímico y farmacológico de especies vegetales utilizadas popularmente en la prevención y tratamiento sintomático de Covid-19 []. PE: Universidad Nacional de Trujillo; 2023. https://hdl.handle.net/20.500.14414/20742
@phdthesis{renati/1044267,
title = "Estudio etnobotánico, fitoquímico y farmacológico de especies vegetales utilizadas popularmente en la prevención y tratamiento sintomático de Covid-19",
author = "Blanco Olano, Cyntia Marysol",
publisher = "Universidad Nacional de Trujillo",
year = "2023"
}
The objective of this research was to determine the ethnobotanical, phytochemical and pharmacological characteristics of plant species used in the prevention and symptomatic treatment of COVID-19 in the La Libertad region. In the study, samples of the studied species of medicinal plants were deposited in the Herbarium truxillense (HUT). The content of phenols and flavonoids was evaluated using spectrophotometric methods. The antioxidant activity was determined by the DPPH, FRAP and ABTS methods. Antibacterial activity was evaluated using the broth microdilution method, culminating in an exploratory UHPLC-MS/MS analysis. 10 plant species were recorded (Cupressus lusitanica Mill. “cipres”, Rosmarinus officinalis L. “rosemary”, Sambucus peruviana Kunth “linden”, Culcitium canescens Humb. & Bonpl. “vira vira”, Stachys byzantina K. Koch “ear of deer”, Perezia multiflora (Humb. & Bonpl.) Less. “scorzonera”, Taraxacum campylodes G.E. Haglund. “dandelion”, Urtica lalibertadensis Weigend “black nettle”, Lepechinia meyenii (Walp.) Epling “sage”, Melissa officinalis L. “lemon balm”), belonging to 5 botanical families, mainly Lamiaceaes and Asteraceaes. The method of preparation according to surveys is by infusion of the entire plant (60%), followed by the leaves and flowers (40%). The phenolic concentration was between the ranges 4.79±0.03 - 144.53±0.05 mg equivalents of gallic acid/g of lyophilized extract (mgEAG/g EL), in the case of flavonoids the ranges obtained were 0.15±0.11 - 73.89±0.12 mg quercetin equivalents/g gram of lyophilized extract (mgEQ/g EL). The antioxidant activity presents values between 53.68±0.54 - 312.32±5.84 mg equivalents of Trolox/g of lyophilized extract (mg ET/g LE). The ranges obtained for antibacterial activity were 0.63 - 5.00 mg/mL. It is concluded that the active substances found in the plants studied can modulate the immune system and have a preventive and supportive therapy as indicated by the sellers, however, further research is required to confirm these hypotheses.
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