Bibliographic citations
Ortega, Y., Aparicio, K. (2021). Prevalencia de la enfermedad del hígado graso no alcohólico (EHGNA) en América Latina y el Caribe: una revisión sistemática [Universidad Peruana Cayetano Heredia]. https://hdl.handle.net/20.500.12866/9720
Ortega, Y., Aparicio, K. Prevalencia de la enfermedad del hígado graso no alcohólico (EHGNA) en América Latina y el Caribe: una revisión sistemática []. PE: Universidad Peruana Cayetano Heredia; 2021. https://hdl.handle.net/20.500.12866/9720
@misc{renati/493854,
title = "Prevalencia de la enfermedad del hígado graso no alcohólico (EHGNA) en América Latina y el Caribe: una revisión sistemática",
author = "Aparicio Barrón, Karina Mercedes",
publisher = "Universidad Peruana Cayetano Heredia",
year = "2021"
}
Background: Non-alcoholic fatty liver disease (NAFLD) produces high morbidity and mortality. Its worldwide prevalence is 25%. The study of its prevalence in LAC is limited, so more evidence is required in this region. Objective: To estimate the prevalence of NAFLD in the adult population of LAC. Materials and methods: For this systematic review we collected data from OVID, Cochrane Library and LILACS search engines. We used terms related to NAFLD and LAC countries. We included observational studies in adults who were born and live in the region. Definitions of NAFLD from each study were accepted. Two reviewers evaluated the articles, extracted data and assessed the risk of bias, discrepancies were resolved by consensus or by a third reviewer. A validated tool was used to assess risk of bias. Results: We analyzed 19 articles (n=5625). The prevalence ranged from 14.3 to 100%. In the subgroup evaluated by abdominal ultrasound it was 14.3 - 73.3% and by liver biopsy, 63 - 100%. In Morbid Obesity patients it was 62.9 - 98.4%, in Diabetes Mellitus II patients it was 69.4 - 83.3% and in postmenopausal women it was 37.1% - 42.1%. The heterogeneity between the studies was high or statistically not significant. Conclusions: We couldn’t find the prevalence of NAFLD in the LAC population or its subgroups due to the great heterogeneity and the lack of studies. Studies with homogeneous definitions are required to quantify the impact of NAFLD in this region.
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